Impact of lymph-node metastasis site in patients with thoracic esophageal cancer

Journal of Surgical Oncology
Chikara KunisakiHirotoshi Akiyama

Abstract

We retrospectively compared surgical outcomes between patients with intra-thoracic and extra-thoracic (cervical and abdominal) lymph-node metastasis. The study population comprised 96 patients with lymph-node metastasis who had undergone curative esophagectomy for thoracic esophageal cancer. The patients were grouped according to whether the site of lymph-node metastasis was intra-thoracic, extra-thoracic, or both intra-thoracic and extra-thoracic. The patient characteristics, survival time, and prognostic factors were compared. The most significant difference in disease-specific survival was detected at a threshold value of four metastatic lymph nodes. Lymph-node metastasis was observed at intra-thoracic sites in 41 patients, at extra-thoracic sites in 20 patients, and at both intra-thoracic and extra-thoracic sites in 35 patients. Intra-thoracic lymph-node metastasis was frequently observed in patients with middle and upper thoracic esophageal cancer. There was no difference in the number of metastatic lymph nodes between patients with intra-thoracic and extra-thoracic lymph-node metastasis. Multivariate analysis revealed that the number of metastatic lymph nodes was an independent prognostic factor, whereas the site of metas...Continue Reading

References

Oct 8, 2005·Cancer Treatment and Research·Yuko KitagawaMasaki Kitajima
Nov 29, 2005·Journal of the American College of Surgeons·Chikara KunisakiHiroshi Shimada
Jul 26, 2006·The Journal of Surgical Research·Hideo ArimaTakashi Aikou
Aug 22, 2006·American Journal of Surgery·Hideaki ShimadaTakenori Ochiai
Dec 5, 2006·The Journal of Thoracic and Cardiovascular Surgery·Nabil RizkUNKNOWN American Joint Committee on Cancer staging system
Mar 27, 2007·The Annals of Thoracic Surgery·Dipok Kumar DharNaofumi Nagasue
Jul 24, 2007·The Annals of Thoracic Surgery·Wayne HofstetterStephen G Swisher
Nov 22, 2007·The Journal of Surgical Research·Matthew WilsonAdam C Berger
Jan 29, 2008·Journal of the American College of Surgeons·Alexander J GreensteinJuan P Wisnivesky
Mar 28, 2009·The Annals of Thoracic Surgery·Chen-Sung LinWen-Hu Hsu

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Citations

Aug 30, 2011·Surgery Today·Yasunori Akutsu, Hisahiro Matsubara
Dec 20, 2011·The Annals of Thoracic Surgery·Jingeng LiuJianhua Fu
Aug 16, 2011·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·B KayaniG B Hanna
Feb 22, 2018·Journal of Clinical Medicine·Tak Kyu OhIn-Ae Song
Dec 19, 2012·Maternal and Child Health Journal·Lindsay A ThompsonJeffrey Roth
Jun 20, 2020·World Journal of Gastroenterology : WJG·Preeti SharmaShanmugarajah Rajendra
Jun 28, 2013·Asian Pacific Journal of Cancer Prevention : APJCP·Ji-Feng FengQi-Xun Chen
May 18, 2013·Asian Pacific Journal of Cancer Prevention : APJCP·Ji-Feng FengQi-Xun Chen

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