Impact of maternal HIV on umbilical cord lactate measurement at delivery in a South African labor ward

International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics
E R AllansonJ E Dickinson

Abstract

To assess umbilical artery lactate levels and perinatal outcomes among women with and without HIV infection. The present prospective cohort study recruited women planning to undergo vaginal delivery at Kalafong Hospital, South Africa, between March 3 and November 12, 2014. Umbilical artery lactate levels were measured and perinatal outcome data were recorded. Outcome analyses were stratified by maternal HIV status, and a subgroup analysis was performed where women with a CD4 count below 350 × 106 cells/L were compared with women without HIV. In total, 936 women with singleton fetuses were enrolled. Maternal HIV status was available for 897 (95.8%) participants, of whom 202 (21.6%) had HIV infections. Overall, 186 (92.1%) women with HIV infections received prophylaxis or treatment. There was no difference between participants with and without HIV infections in the preterm delivery rate (P=0.770), mode of delivery (P=0.354), neonatal resuscitation rate (P=0.717), 1- or 5-minute Apgar scores below 7 (P=0.353), or the rate of having an umbilical artery lactate level above 5.45 mmol/L (P=0.301). Similarly, there were no differences in outcomes in the subgroup analysis of women with a CD4 count below 350 × 106 cells/L. Umbilical arte...Continue Reading

References

Jul 27, 2007·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·P El-BeituneL C Rodrigues
Jun 16, 2009·European Journal of Applied Physiology·Carlo BaldariLaura Guidetti
Jul 16, 2010·Archives of Gynecology and Obstetrics·Yun WangTore Henriksen
Aug 19, 2010·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Christopher R H WhiteCraig E Pennell
Apr 19, 2011·Lancet·Joy E LawnUNKNOWN Lancet's Stillbirths Series steering committee
Oct 12, 2013·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Christopher R H WhiteCraig E Pennell
Apr 22, 2014·American Journal of Obstetrics and Gynecology·Robert D StewartJeanne S Sheffield
Mar 10, 2016·Obstetrics and Gynecology·Methodius G TuuliAlison G Cahill
Oct 6, 2016·BJOG : an International Journal of Obstetrics and Gynaecology·E R AllansonJ E Dickinson
Apr 5, 2017·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·E R AllansonJ E Dickinson

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