Impact of mediastinal lymph node dissection on octogenarians with non-small cell lung cancer.

The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai Zasshi
Shinjiro MizuguchiShigefumi Suehiro

Abstract

Impacts of mediastinal lymph node dissection on a patient's course after pulmonary resection is unclear in octogenarians with non-small cell lung cancer. Retrospectively identified subjects included 39 octogenarians and 1 nonagenarian, with grades according to the Charlson Comorbidity Index ranging from only 0 to 2. We performed mediastinal lymph node dissection in 19 patients (D group), and just lymph node sampling biopsy in the other 21 (S group). We compared clinicopathologic features and outcome after surgery between both groups. Deterioration of performance status at the time of discharge, evident in 17 patients overall, was significantly more frequent in the D group. Postoperative complications occurred in 27 patients overall and there was no significant difference between the two groups. Survival rates in younger patients at 1, 3, and 5 years were 86, 59, and 49%, respectively; in octogenarians these were 83, 58, and 42% (no significant difference). Nor did survival differ significantly by surgical management of mediastinal lymph nodes; 1-, 3-, and 5-year survival rates were 94, 63, and 40%, respectively in the D group and 78, 66, and 43%, respectively in the S group. Octogenarians with non-small cell lung cancer should ...Continue Reading

References

Dec 1, 1990·Hematology/oncology Clinics of North America
Dec 1, 1990·The Annals of Thoracic Surgery·T IshidaK Sugimachi
Oct 1, 1987·The Surgical Clinics of North America·N Martini, B J Flehinger
Jan 1, 1994·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·K S NaunheimD R Judd
Jan 1, 1994·The Annals of Thoracic Surgery·T OsakiH Ueda
Jul 1, 1993·European Journal of Cancer. Part B, Oral Oncology·I R KramerM Shear
Jan 1, 1993·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·P ThomasP Fuentes
Mar 1, 1997·The Annals of Thoracic Surgery·S PagniR B Ponn
Mar 1, 1997·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·U MorandiR Lodi
Oct 8, 1997·Cancer·D B Reuben
Feb 6, 1998·The Journal of Thoracic and Cardiovascular Surgery·H WadaY Watanabe
Jun 17, 1998·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·P ThomasJ Deslauriers
Sep 3, 1998·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·S PagniR B Ponn
Apr 27, 1999·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·T HanagiriK Yasumoto
Aug 3, 1999·The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai Zasshi·T TanitaS Fujimura
Dec 13, 2000·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·T AokiT Hirono
Mar 13, 2002·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·V Zagonel
Apr 16, 2003·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Tadashi AokiJun-ichi Hayashi
Jan 17, 2004·The Annals of Thoracic Surgery·Malcolm V BrockStephen C Yang
Sep 15, 2004·Chest·Jeffrey L PortNasser K Altorki
Dec 1, 1992·The Journal of Primary Prevention·J L Pedro-CarrollE L Cowen

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Citations

Jun 4, 2010·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Elizabeth M BlanchardPaul J Hesketh
Jan 5, 2016·Clinical Lung Cancer·Apar Kishor GantiAnne Kessinger
Jan 2, 2008·Revue de pneumologie clinique·C FoucaultM Riquet
Oct 4, 2013·Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia·Yuzuru WatanabeHiroyuki Suzuki
Dec 23, 2017·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Haruaki HinoJun Nakajima
Feb 3, 2007·Current Opinion in Oncology·Lorenzo Spaggiari, Paolo Scanagatta
Sep 3, 2010·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Elizabeth A BallegeerNicholas S Keuler
Nov 8, 2018·The Korean Journal of Thoracic and Cardiovascular Surgery·Seokbeom HongJae Kil Park

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