Impact of metabolic syndrome and its individual components on the presence and severity of angiographic coronary artery disease.

Yonsei Medical Journal
Jong-Youn KimHyuck Moon Kwon

Abstract

Metabolic syndrome (MS) has been reported as a potential risk factor of coronary artery disease (CAD). The aims of this study were to assess whether there was a relationship between MS score and CAD angiographic severity, and to assess the predictive value of individual components of MS for CAD. We retrospectively enrolled 632 patients who underwent coronary angiography for suspected CAD (394 men, 61.0 +/- 10.6 years of age). MS was defined by the National Cholesterol Education Program criteria with the waist criterion modified into a body mass index (BMI) of more than 25 kg/m(2). The MS score defined as the number of MS components. CAD was defined as > 50% luminal diameter stenosis of at least one major epicardial coronary artery. CAD angiographic severity was evaluated with a Gensini scoring system. Of the patients, 497 (78.6%) had CAD and 283 (44.8%) were diagnosed with MS. The MS score was significantly related to the Gensini score. High fasting blood glucose (FBG) was the only predictive factor for CAD. A cluster including high FBG, high blood pressure (BP), and low high-density lipoprotein cholesterol (HDL-C) showed the highest CAD risk. The MS score correlates with the angiographic severity of CAD. The predictive ability...Continue Reading

References

Feb 1, 1983·The American Journal of Cardiology·G G Gensini
Apr 4, 1998·The American Journal of Cardiology·S M Grundy
May 23, 2001·JAMA : the Journal of the American Medical Association·UNKNOWN Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
May 29, 2004·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Philip T JamesUNKNOWN International Obesity Task Force
Sep 24, 2004·Diabetic Medicine : a Journal of the British Diabetic Association·Marit Eika Jørgensen, Knut Borch-Johnsen
Aug 2, 2005·Journal of Cardiopulmonary Rehabilitation·Karine MarquisPaul Poirier
Dec 14, 2005·Circulation·Philip Greenland
Mar 1, 2006·Archives of Internal Medicine·Maija HassinenRainer Rauramaa
Mar 2, 2006·Journal of Hypertension·Markus ClemenzThomas Unger
Jun 1, 2006·The Journal of Clinical Endocrinology and Metabolism·James B MeigsRalph B D'Agostino
Sep 27, 2006·The American Journal of Medicine·Andrea GalassiJiang He
Nov 8, 2007·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·H S ParkH J Yoo

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Citations

Apr 29, 2014·PloS One·Silas J LeavesleyPetra Rocic
Dec 19, 2013·North American Journal of Medical Sciences·Mukund P SrinivasanChakrapani Mahabala
Jul 30, 2014·Metabolic Syndrome and Related Disorders·Ebenezer Adekunle AjayiOlatayo Adekunle Adeoti
Jul 26, 2012·Experimental Diabetes Research·Rebecca Hutcheson, Petra Rocic
Jan 17, 2012·The Canadian Journal of Cardiology·Jung-Jung ChangShih-Tai Chang
Jun 7, 2011·Revista española de cardiología·Ana JoverAntonio Hernández-Mijares
Jan 24, 2014·Journal of Atherosclerosis and Thrombosis·Sunghwan Suh, Moon-Kyu Lee
May 26, 2017·Diabetology & Metabolic Syndrome·Theodora W ElffersStella Trompet
Mar 19, 2020·BMC Public Health·Elvia Cristina Mendoza-CaamalLorena Orozco
Mar 7, 2021·International Journal of Environmental Research and Public Health·Amal F AlshammaryImran Ali Khan
Jul 22, 2021·Journal of Cardiovascular Translational Research·Jill K BadinMichael Sturek

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