Impact of metabolic syndrome on the outcomes of superficial femoral artery interventions

Journal of Vascular Surgery
Christopher J SmolockMark G Davies

Abstract

Metabolic syndrome (MetSyn) is an epidemic in the United States and is associated with early onset of atherosclerosis, increased thrombotic events, and increased complications after cardiovascular intervention. MetSyn is found in ∼50% of patients with peripheral vascular disease. However, its impact on peripheral interventions is unknown. The aim of this study is to determine the outcomes of superficial femoral artery (SFA) interventions in patients with and without MetSyn. A database of patients undergoing endovascular treatment of SFA disease between 1999 and 2009 was retrospectively queried. MetSyn was defined as the presence of ≥3 of the following criteria: blood pressure ≥130 mm Hg/≥85 mm Hg; triglycerides ≥150 mg/dL; high-density lipoprotein ≤50 mg/dL for women and ≤40 mg/dL for men; fasting blood glucose ≥110 mg/dL; or body mass index ≥30 kg/m(2). Kaplan-Meier survival analyses were performed to assess time-dependent outcomes. Factor analyses were performed using a Cox proportional hazard model for time-dependent variables. A total of 1018 limbs in 738 patients (64% male, average age 67 years) underwent endovascular treatment for symptomatic SFA disease with 45% of patients meeting the criteria for MetSyn. MetSyn patient...Continue Reading

References

Oct 6, 1997·Journal of Vascular Surgery·R B RutherfordD N Jones
Jan 16, 2002·JAMA : the Journal of the American Medical Association·Earl S FordWilliam H Dietz
Jan 9, 2004·Endocrinology and Metabolism Clinics of North America·Carol A Maggio, F Xavier Pi-Sunyer
Mar 16, 2005·Journal of Vascular Surgery·Scott M SurowiecRichard M Green
Jul 26, 2005·Journal of the American College of Surgeons·Mark G DaviesThomas A Pearson
Feb 14, 2006·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Alan B Lumsden, Tony S Das
Jul 26, 2006·Annals of Vascular Surgery·Evan J RyerPeter L Faries
Nov 28, 2006·Circulation Journal : Official Journal of the Japanese Circulation Society·Takatoshi KasaiHiroyuki Daida
Jan 16, 2007·Journal of Vascular Surgery·L NorgrenUNKNOWN TASC II Working Group
Nov 6, 2007·Journal of Vascular Surgery·Andrew M BakkenMark G Davies
Mar 25, 2008·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Takatoshi KasaiHiroyuki Daida
Apr 30, 2008·Metabolism: Clinical and Experimental·Paola CanibusRoberto Piva
Jul 22, 2008·Annals of Vascular Surgery·Mark G DaviesAlan B Lumsden
Aug 30, 2008·Journal of Vascular Surgery·Mark G DaviesAlan B Lumsden
Oct 29, 2008·Advances in Surgery·Larisse K Lee, K Craig Kent
Jan 9, 2009·Annals of Vascular Surgery·Andrew M BakkenMark G Davies
Jan 17, 2009·Angiology·Milos MaksimovicJagoda Jorga
Apr 28, 2009·Journal of Vascular Surgery·Clinton D ProtackMark G Davies
Jun 2, 2009·Journal of Vascular Surgery·Philip P GoodneyRobert M Zwolak
Jul 25, 2009·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Alan B LumsdenEric K Peden
Aug 25, 2009·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·G BrevettiM Chiariello
Dec 22, 2009·Journal of Vascular Surgery·Mark G DaviesAlan B Lumsden
Apr 30, 2010·Diabetes Research and Clinical Practice·Jeong Su KimYeong Dae Kim
Jan 20, 2012·Cardiorenal Medicine·James R SowersMelvin R Hayden

❮ Previous
Next ❯

Citations

Dec 29, 2013·Annals of Vascular Surgery·Dean J ArnaoutakisChristopher J Abularrage
May 16, 2014·Microcirculation : the Official Journal of the Microcirculatory Society, Inc·Joshua T ButcherJefferson C Frisbee
Sep 28, 2015·Journal of Vascular Surgery·Mark G Davies, Hosam F El-Sayed
Jun 26, 2015·British Journal of Anaesthesia·P TzimasG Papadopoulos
Jun 8, 2013·Atherosclerosis·Jonathan GolledgeMaggie A Cunningham
Jun 29, 2014·The Journal of Surgical Research·Yuyang FuMark G Davies
Mar 29, 2014·Circulation Journal : Official Journal of the Japanese Circulation Society·Soichiro EbisawaUichi Ikeda
Oct 11, 2014·Annals of Vascular Surgery·Christopher J SmolockMark G Davies
Aug 20, 2015·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Mark G Davies, Hosam F El-Sayed

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carotid Artery Diseases

Carotid artery disease is a group of pathological conditions of the carotid artery. Discover the latest research on carotid artery disease here.