Impact of MLC properties and IMRT technique in meningioma and head-and-neck treatments
Abstract
The impact of multileaf collimator (MLC) design and IMRT technique on plan quality and delivery improvements for head-and-neck and meningioma patients is compared in a planning study. Ten previously treated patients (5 head-and-neck, 5 meningioma) were re-planned for step-and-shoot IMRT (ssIMRT), sliding window IMRT (dMLC) and VMAT using the MLCi2 without (-) and with (+) interdigitation and the Agility-MLC attached to an Elekta 6MV linac. This results in nine plans per patient. Consistent patient individual optimization parameters are used. Plans are generated using the research tool Hyperion V2.4 (equivalent to Elekta Monaco 3.2) with hard constraints for critical structures and objectives for target structures. For VMAT plans, the improved segment shape optimization is used. Critical structures are evaluated based on QUANTEC criteria. PTV coverage is compared by EUD, Dmean, homogeneity and conformity. Additionally, MU/plan, treatment times and number of segments are evaluated. As constrained optimization is used, all plans fulfill the hard constraints. Doses to critical structures do not differ more than 1 Gy between the nine generated plans for each patient. Only larynx, parotids and eyes differ up to 1.5 Gy (Dmean or Dmax)...Continue Reading
References
Characterization of a commercial multileaf collimator used for intensity modulated radiation therapy
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