Impact of mode of delivery on markers of perinatal hemodynamics in infants with hypoplastic left heart syndrome

The Journal of Pediatrics
Amy L PetersonJ Rychik

Abstract

To determine whether the mode of delivery of infants prenatally diagnosed with hypoplastic left heart syndrome (HLHS) affects markers of perinatal hemodynamics. A retrospective review of patients diagnosed prenatally with HLHS and delivered within our institution was undertaken. Arterial blood gases, echocardiographic data, and markers of end organ function were compared based on route of delivery. A total of 79 infants with HLHS were enrolled between January 2002 and December 2008. The infants delivered by elective cesarian delivery (CD) had younger gestational age compared with those delivered by vaginal delivery (VD) or by urgent CD/operative VD. Those delivered by elective CD had lower pH and higher partial pressure of CO(2) on arterial cord blood gas analysis. There were no differences in partial pressure of O(2) and base deficit among the 3 study groups. One-minute and 5-minute Apgar scores, markers of end organ function, echocardiographic parameters, length of hospitalization, and survival to discharge were similar among the groups. Overall, newborns with a prenatal diagnosis of HLHS transitioned well to extrauterine life without significant acidosis regardless of the mode of delivery. Delivery of newborns with HLHS by e...Continue Reading

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Citations

May 31, 2014·Journal of Perinatology : Official Journal of the California Perinatal Association·C A WalshF M McAuliffe
Mar 17, 2015·Frontiers in Pediatrics·Antonio Francesco Corno
Nov 29, 2016·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Takekazu MiyoshiTomoaki Ikeda
Jul 12, 2017·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Aline WolterRoland Axt-Fliedner
Apr 26, 2014·Circulation·Mary T DonofrioAmerican Heart Association Adults With Congenital Heart Disease Joint Committee of the Council on Cardiovascular Disease in
Apr 14, 2016·Journal of Perinatal Medicine·Tuangsit WataganaraMiroslaw Wielgos
Oct 16, 2019·Journal of Perinatology : Official Journal of the California Perinatal Association·April D AdamsSara N Iqbal

Related Concepts

Apgar Score
Blood Gas Analysis
Blood Glucose
Ampholytes
Carbon Dioxide
Postcesarean Section
Krebiozen
Prevalence Studies
2D Echocardiography
Umbilical Cord Blood

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