Impact of Mother-Infant Pair Clinics and Short-Text Messaging Service (SMS) Reminders on Retention of HIV-Infected Women and HIV-Exposed Infants in eMTCT Care in Malawi: A Cluster Randomized Trial

Journal of Acquired Immune Deficiency Syndromes : JAIDS
Victor MwapasaAndrews Gunda

Abstract

Poor retention of mothers and HIV-exposed infants (HEIs) in HIV care threatens efforts to eliminate pediatric HIV. Novel strategies are required to address this challenge. We compared 12-month maternal and HEI postpartum retention in health facilities implementing the following HIV care delivery models: integrated HIV and maternal, neonatal, and child health services [mother-infant pair (MIP) clinics], MIP clinics plus short-text messaging service (SMS) reminders to prevent default (MIP + SMS), and standard of care (SOC). From May 2013 to August 2016, a cluster randomized trial was conducted in rural Malawi, which randomized 30 health facilities to the 3 service delivery models. HIV+ pregnant women and HEIs were enrolled and followed up to monitor compliance with prescheduled visits and retention. Log binomial regression, using generalized estimated equation, was used to assess the impact of the models on retention. The trial enrolled 461, 493, and 396 HIV+ pregnant women and 386, 399, and 300 HEIs into the MIP, MIP + SMS, and SOC arms, respectively. Compared with the 12-month maternal retention rate in the SOC arm (22.2%), the rates were similar in the MIP arm [19.3%, risk ratio (RR): 0.85, 95% confidence interval (CI): 0.56 t...Continue Reading

References

Oct 16, 2004·Journal of Clinical Epidemiology·Geoffrey AdamsMichael J Campbell
Apr 11, 2012·Tropical Medicine & International Health : TM & IH·Ralf WeigelSam Phiri
Jan 29, 2014·AIDS·Lyson TenthaniUNKNOWN Ministry of Health in Malawi and IeDEA Southern Africa
Aug 5, 2014·Tropical Medicine & International Health : TM & IH·Hannock TweyaSam Phiri
Jun 18, 2016·Journal of the International AIDS Society·Leila KatirayiThorkild Tylleskär
Dec 9, 2016·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Yael Hirsch-MovermanAndrea A Howard
Jan 4, 2017·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Fabian CataldoUNKNOWN PURE Malawi Consortium
May 13, 2017·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Andrews GundaVictor Mwapasa

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Citations

May 13, 2017·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Andrews GundaVictor Mwapasa
Jul 12, 2018·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Surbhi ModiHelen Dale
Nov 7, 2018·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Ruby N FayorseyElaine J Abrams
May 13, 2017·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Nigel C RollinsGottfried O Hirnschall
Dec 30, 2017·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Brandon A KnettelMelissa H Watt
Aug 12, 2020·The Cochrane Database of Systematic Reviews·Melissa J PalmerCaroline Free
Aug 20, 2020·The Cochrane Database of Systematic Reviews·Melissa J PalmerCaroline Free
Oct 9, 2020·Journal of the International AIDS Society·Helene FontUNKNOWN INSPIRE group
Apr 20, 2021·Journal of Acquired Immune Deficiency Syndromes : JAIDS·I Marion Sumari-de BoerRob E Aarnoutse

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