Impact of multiple micronutrient versus iron-folic acid supplements on maternal anemia and micronutrient status in pregnancy.

Food and Nutrition Bulletin
Lindsay H AllenMaternal Micronutrient Supplementation Study Group

Abstract

Multiple micronutrient supplements could increase hemoglobin and improve micronutrient status of pregnant women more than iron supplements alone or iron with folic acid. To compare the effects of multiple micronutrients with those of iron supplements alone or iron with folic acid, on hemoglobin and micronutrient status of pregnant women. Studies were identified in which pregnant women were randomized to treatment with multiple micronutrients, or with iron with or without folic acid. A pooled analysis was conducted to compare the effects of these supplements on maternal hemoglobin, anemia, and micronutrient status. Effect size was calculated for individual and combined studies, based on mean change from baseline to final measure in the group receiving iron, with or without folic acid, minus the mean change in the group, divided by the pooled standard deviation of the two groups. The effect on the relative risk of anemia or iron deficiency was calculated as the probability of anemia or iron deficiency in the group receiving multiple micronutrients divided by the probability in the group receiving iron, with or without folic acid. Multiple micronutrient supplements had the same impact on hemoglobin and iron status indicators as ir...Continue Reading

References

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Citations

Feb 4, 2010·Food and Nutrition Bulletin·Caroline H D FallUNKNOWN Maternal Micronutrient Supplementation Study Group
Nov 20, 2012·Journal of Dietary Supplements·Catherine UlbrichtSara Zhou
Jul 7, 2012·Paediatric and Perinatal Epidemiology·Usha RamakrishnanZulfiqar Ahmed Bhutta
Jan 16, 2014·Journal of Food Science and Technology·A Rajasekaran, M Kalaivani
Apr 14, 2011·Nutrition Research and Practice·Ted Greiner
Feb 3, 2012·The Journal of Nutrition·Dominique RoberfroidPatrick Kolsteren
Feb 4, 2010·Food and Nutrition Bulletin·Carine RonsmansUNKNOWN Maternal Micronutrient Supplementation Study Group
Jul 7, 2012·Paediatric and Perinatal Epidemiology·Zulfiqar A BhuttaReynaldo Martorell
Mar 13, 2015·Nutrients·Ian Darnton-Hill, Uzonna C Mkparu
Mar 4, 2011·The American Journal of Clinical Nutrition·Dominique RoberfroidUNKNOWN MISAME Study Group
Jan 31, 2019·The Cochrane Database of Systematic Reviews·Ana C Fernández-Gaxiola, Luz Maria De-Regil
Apr 29, 2011·BMC Public Health·Batool Azra HaiderZulfiqar A Bhutta

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