Impact of Nesiritide Infusion on Early Postoperative Recovery After Total Cavopulmonary Connection Surgery

Pediatric Cardiology
Yajuan ZhangHaitao Xu

Abstract

The purpose of the study is to compare the effects of nesiritide on the discharge time and pleural effusion in children with total cavopulmonary connection (TCPC), and to provide a more reasonable clinical method for these children. Forty-four who children underwent cavopulmonary connection between January 2016 and 2017 were retrospectively collected, and 5 children were excluded from analysis due to postoperative thrombosis or second Fontan surgery due to high pulmonary hypertension. Thirteen children received nesiritide (3-11 days) plus conventional treatment as the nesiritide group, continuous infusion of nesiritide with the dose of 0.01 ug kg-1 min-1. Twenty-six children with the conventional treatment as the conventional treatment group. The length of stay in hospital and the retention time of chest drainage tube were compared between two groups. There were no significant differences in the time of cardiopulmonary bypass, postoperative ventilation time, ICU time, and vasoactive inotropic drug scores in the two groups. There were no hospital deaths in two groups. The median hospital stay was 20 days in the nesiritide group (11-56 days, means 25 days), and the median length of hospital stay was 28 days in the routine treatme...Continue Reading

References

Feb 1, 1992·Circulation·D J DriscollG K Danielson
Aug 1, 1996·Journal of the American College of Cardiology·F CettaG K Danielson
Jul 27, 1999·The Annals of Thoracic Surgery·T HiramatsuM Nakazawa
Jan 11, 2003·American Journal of Physiology. Heart and Circulatory Physiology·Savio P D'SouzaGary F Baxter
May 4, 2005·The Journal of Thoracic and Cardiovascular Surgery·Lena S SunJan M Quaegebeur
Sep 9, 2005·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·William T MahleJanet M Simsic
Sep 13, 2005·The Journal of Thoracic and Cardiovascular Surgery·John M CostelloDenise M Goodman
May 16, 2006·Journal of Intensive Care Medicine·Janet M SimsicRobert E Michler
Dec 13, 2006·Journal of the American College of Cardiology·Peter J BartzFrank Cetta
Feb 13, 2007·Journal of the American College of Cardiology·Robert M MentzerUNKNOWN NAPA Investigators
Sep 11, 2007·Journal of Cardiac Failure·John L JefferiesJeffrey A Towbin
Sep 23, 2008·Journal of Intensive Care Medicine·Janet M SimsicKevin O Maher
Jul 8, 2011·The New England Journal of Medicine·C M O'ConnorR M Califf
Oct 4, 2014·The Journal of Thoracic and Cardiovascular Surgery·Robert J DabalYung Lau

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Related Papers

European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
Souheir SalamAlessandro Giardini
© 2022 Meta ULC. All rights reserved