Impact of Norwood versus hybrid palliation on cardiac size and function in hypoplastic left heart syndrome

Heart
Heynric B GrotenhuisLuc Mertens

Abstract

The hybrid approach for hypoplastic left heart syndrome (HLHS) could theoretically result in better preservation of right ventricular (RV) function then the Norwood procedure. The aim of this study was to compare echocardiographic indices of RV size and function in patients after Norwood and hybrid throughout all stages of palliation. 76 HLHS patients (42 Norwood, 34 hybrid) were retrospectively studied. Echocardiography was obtained before stage I, before and after stage II, and before and after Fontan. Median follow-up was 4.9 years (range 1.1-8.5). Baseline characteristics before stage I were similar. Hybrid patients demonstrated a significant decrease in RV fractional area change (FAC) between baseline and pre-stage II (36±9% vs 27±6%; p<0.01); Norwood patients remained stable (32±10% vs 32±7%; p=0.21). At pre-stage II, moderate/severe tricuspid valve (TV) regurgitation was found in nine Norwood (33%) and four hybrid (18%) patients (p=0.19). After stage II, the difference in FAC became insignificant (29±7% vs 25±8%, p=0.08) and moderate/severe TV regurgitation (TR) was found in 13 Norwood (48%) and four hybrid patients (19%) (p=0.18). At pre-Fontan, RV FAC was similar after Norwood and hybrid (34±5% vs 33±6%, p=0.69), which...Continue Reading

References

Nov 24, 2004·Journal of Applied Physiology·Thierry Sluysmans, Steven D Colan
Jan 10, 2006·The Journal of Thoracic and Cardiovascular Surgery·Emile A BachaZiyad M Hijazi
Sep 25, 2007·The Annals of Thoracic Surgery·Christopher A CaldaroneGlen S Van Arsdell
May 24, 2008·The Annals of Thoracic Surgery·Mark GalantowiczRoberta Rodeman
Jul 11, 2009·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Takahisa SakuraiYuichi Ueda
Feb 1, 2012·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Walter KnirschBeatrice Latal
Sep 22, 2012·Circulation·Kenji BabaOsami Honjo
Jul 24, 2013·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Tara BharuchaMark K Friedberg

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Citations

Mar 17, 2018·World Journal for Pediatric & Congenital Heart Surgery·Jacob Y CaoDavid S Winlaw
Jul 18, 2018·Circulation. Cardiovascular Imaging·Jae Sung SonMark K Friedberg
Dec 30, 2020·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Kandice MahTimothy Colen
May 15, 2021·Pediatric Cardiology·Sowmya BalasubramanianRajesh Punn

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