Impact of obstructive sleep apnoea on clinical characteristics and outcomes in patients with acute coronary syndrome following percutaneous coronary intervention

The Journal of International Medical Research
S MengX-H Huang

Abstract

This study tested whether obstructive sleep apnoea syndrome (OSAS) influenced clinical characteristics and outcomes after successful percutaneous coronary intervention (PCI) in 123 consecutive patients with acute coronary syndrome (ACS). Patients with an apnoea-hypopnea index (AHI) >or= 5 were considered as having OSAS. Carotid ultrasonography and echocardiography were performed, and C-reactive protein (CRP) and fibrinogen were measured. Co-existence of ACS and OSAS occurred in 76 patients (61.8%) and patients with OSAS had a greater interventricular septum thickness (IVST) and higher levels of CRP than non-OSAS patients. In an elderly subpopulation (>or= 75 years of age), two-vessel disease was significantly more common and fibrinogen levels were significantly higher in OSAS than non-OSAS patients. Carotid intima-media thickness (IMT) correlated with the AHI in ACS patients. In elderly ACS patients, IMT, Gensini score and fibrinogen correlated with AHI. Patients were followed up for 1 year for major adverse cardiac events (MACEs) and no significant difference in major MACEs was found after this period between OASAS and non-OSAS patients. This study indicates that OSAS is associated with inflammation and increased IVST in ACS p...Continue Reading

References

Aug 1, 1988·The American Review of Respiratory Disease·E WeitzenblumD Kurtz
Sep 1, 1983·The American Journal of Cardiology·C GuilleminaultR A Winkle
Apr 29, 1993·The New England Journal of Medicine·T YoungS Badr
Jun 1, 1993·The American Journal of Cardiology·P HanlyK Lunn
Mar 7, 2000·Cardiology·H SchäferB Lüderitz
Apr 19, 2000·JAMA : the Journal of the American Medical Association·F J NietoT G Pickering
Jul 19, 2000·American Journal of Physiology. Heart and Circulatory Physiology·B G PhillipsV K Somers
Jul 21, 2000·American Journal of Respiratory and Critical Care Medicine·Y PekerS Löth
Dec 6, 2001·American Journal of Respiratory and Critical Care Medicine·T MooeU Wiklund
Apr 6, 2002·American Journal of Respiratory and Critical Care Medicine·Larissa DyugovskayaLena Lavie
May 16, 2003·JAMA : the Journal of the American Medical Association·Aram V ChobanianUNKNOWN National High Blood Pressure Education Program Coordinating Committee
Sep 4, 2003·The European Respiratory Journal·I A HarschJ H Ficker
Mar 5, 2004·Sleep·Takahiro SuzukiHiroshi Kimura
Apr 29, 2004·JAMA : the Journal of the American Medical Association·Terry YoungPaul E Peppard
Mar 4, 2006·American Journal of Respiratory and Critical Care Medicine·Kengo UsuiT Douglas Bradley
Apr 27, 2007·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Hai-Ya WangDing-Liang Zhu
Mar 28, 2008·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·A G P de SousaA Halpern
Oct 24, 2008·Archives of Physiology and Biochemistry·Silke Ryan, Walter T McNicholas
Jan 20, 2009·Cardiovascular & Hematological Agents in Medicinal Chemistry·Silke Ryan, Walter T McNicholas

❮ Previous
Next ❯

Citations

Sep 26, 2013·International Journal of Vascular Medicine·Rashid NadeemNayab Navid
Aug 24, 2016·Sleep & Breathing = Schlaf & Atmung·Zhuoshan HuangJinlai Liu
Jun 12, 2018·Trauma, Violence & Abuse·Kader Tekkas Kerman, Patricia Betrus
Jun 28, 2020·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·Hong WangGuoping Gong
Nov 8, 2017·American Journal of Respiratory and Critical Care Medicine·R Nisha AuroraNaresh M Punjabi
May 29, 2018·Experimental and Therapeutic Medicine·Jidong ZhangWenzhong Zhang
Mar 27, 2020·BMC Cardiovascular Disorders·Michael R Le GrandeAlun C Jackson
Jan 15, 2019·Journal of the American Heart Association·Jingyao FanYongxiang Wei

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.