Impact of partial reimbursement on hepatitis B antiviral utilization and adherence

World Journal of Gastroenterology : WJG
Qian QiuLi Wang

Abstract

To determine the impact of partial reimbursement for antivirals on antiviral utilization and adherence for chronic hepatitis B patients. This was a retrospective cohort study. Two separate cohorts were enrolled, including 14163 and 16288 chronic hepatitis B outpatients, respectively. These patients were referred to Beijing You'an Hospital before and after the new partial reimbursement for antivirals, which was implemented on July 1, 2011. Demographic characteristics (including medical insurance status), routine biochemical, virological and serology laboratory test results, and antiviral agents' prescription information were collected from an electronic database. Patients were also defined as new and existing patients according to treatment history. Antiviral utilization, medication possession ratio and persistence rate were calculated and compared among the patients with different characteristics. A questionnaire survey was conducted among 212 randomly sampled outpatients from the same hospital to confirm the validity of the electronic database. Propensity score matching was used to adjust the distribution of patient's characteristics which may influence the antiviral utilization. χ(2) test or ANOVA was adopted and multivariate...Continue Reading

References

Jul 6, 2000·Annals of Internal Medicine·D L PatersonN Singh
Oct 27, 2001·Journal of Clinical Pharmacy and Therapeutics·E VermeireJ Denekens
Mar 5, 2003·Seminars in Liver Disease·Giovanna Fattovich
Aug 5, 2005·The New England Journal of Medicine·Lars Osterberg, Terrence Blaschke
Mar 4, 2006·Pharmacoepidemiology and Drug Safety·Susan E AndradeK Arnold Chan
Apr 21, 2006·Journal of Managed Care Pharmacy : JMCP·Thomas J BramleyFeride Frech-Tamas
Jan 12, 2007·British Journal of Clinical Pharmacology·Marie-Hélène BouchardSylvie Perreault
Jan 31, 2007·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Andrew M PetersonMichael Nichol
Aug 29, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Anna S F Lok, Brian J McMahon
Oct 5, 2010·Journal of Hepatology·Watcharasak ChotiyaputtaAnna S F Lok
Oct 19, 2010·Journal of Hepatology·Maximilian Lee, Emmet B Keeffe
Jan 22, 2011·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Yun-Fan LiawEugene R Schiff
Mar 23, 2012·Journal of Hepatology·UNKNOWN European Association For The Study Of The Liver
Apr 28, 2012·Gastroenterology·Steven J Scaglione, Anna S F Lok

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.