Impact of patient-prosthesis mismatch on 30-day outcomes in young and middle-aged patients undergoing aortic valve replacement.

Journal of Cardiothoracic Surgery
Daniel Hernandez-VaqueroFrancisco Boye

Abstract

The impact of patient-prosthesis mismatch (PPM) on early outcomes in young and middle-aged patients undergoing conventional aortic valve replacement for severe aortic stenosis remains unknown. Our objective was to evaluate the incidence of some degree of PPM and its influence on early mortality and morbidity. We analyzed our single center experience in all patients <70 years undergoing first-time isolated aortic valve replacement for severe stenosis in our center from September 2007 to September 2011. PPM was defined as an indexed effective orifice area ≤ 0,85 cm(2)/m(2). The influence of PPM on early mortality and postoperative complications was studied using propensity score analysis. Follow up at 30 postoperative days was 100% complete. Of 199 patients studied, 61 (30,7%) had some degree of PPM. PPM was associated with an increased postoperative mortality (OR = 8,71; 95% CI = 1,67-45,29; p = 0,04) and major postoperative complications (OR = 2,96; CI = 1,03-8,55; p = 0,044). However, no association between PPM and prolonged hospital or ICU stay was demonstrated. Moderate PPM is a common finding in young and middle-aged patients undergoing surgery for aortic valve replacement due to severe stenosis. In addition, its influence ...Continue Reading

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Citations

Apr 19, 2013·Journal of Cardiothoracic Surgery·Bart M KoeneAlbert H van Straten
Oct 18, 2013·General Thoracic and Cardiovascular Surgery·Kentaro Honda, Yoshitaka Okamura
Feb 21, 2016·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Igor TudoracheAxel Haverich
Feb 19, 2014·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Ajay YadlapatiGabriel Vorobiof
Apr 11, 2017·Annals of Cardiac Anaesthesia·Kathirvel Subramaniam, Soheyla Nazarnia
Mar 9, 2019·Heart·Rajdeep BilkhuCatherine M Otto
Jan 5, 2019·The Thoracic and Cardiovascular Surgeon·Paulo A AmorimTorsten Doenst
Jan 1, 2019·Indian Journal of Thoracic and Cardiovascular Surgery : Official Organ, Association of Thoracic and Cardiovascular Surgeons of India·Abid IqbalJayakumar Karunakaran
Jun 9, 2016·Open Access Macedonian Journal of Medical Sciences·Selman DumaniAli Refatllari
Jun 4, 2021·Perfusion·Serik AitaliyevRimantas Benetis

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