Impact of phosphatidylethanolamine on the antioxidant activity of α-tocopherol and trolox in bulk oil

Journal of Agricultural and Food Chemistry
Leqi CuiEric A Decker

Abstract

The amphiphilic phospholipids dioleoylphosphatidylcholine (DOPC) and dioleoylphosphatidylethanolamine (DOPE), can form reverse micelles in bulk oils, which affects lipid oxidation chemistry. Previous studies showed that reverse micelles formed by DOPC and DOPE shorten the oxidation lag phase of stripped soybean oil. This study examined how these reverse micelles influence the activity of primary antioxidants such as the nonpolar α-tocopherol and the polar trolox in stripped and commercial soybean oils. The results showed that DOPC reverse micelles decreased the activity of 100 μM α-tocopherol or trolox. On the other hand, DOPE increased the antioxidant activity of both α-tocopherol and trolox. The polar trolox exhibited better antioxidant activity than the nonpolar α-tocopherol in the presence of both DOPC and DOPE reverse micelles because trolox partitioned more at the interfaces, which was confirmed by a fluorescence steady state study. Different ratios of DOPE to DOPC were added to oil containing 100 μM α-tocopherol, and antioxidant activity increased with increasing DOPE/DOPC ratio. Addition of DOPE to commercial oil inhibited lipid oxidation, whetrsd DOPC was ineffective. HPLC showed that DOPE regenerated α-tocopherol. Thi...Continue Reading

References

Feb 1, 1975·Journal of the American Oil Chemists' Society·A L Branen
Oct 1, 1986·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·N ItoM Tatematsu
Jan 1, 1993·Toxicology and Industrial Health·W L Porter
Feb 3, 2005·Journal of Agricultural and Food Chemistry·Francisco J HidalgoRosario Zamora
Feb 26, 2005·Critical Reviews in Food Science and Nutrition·Rosario Zamora, Francisco J Hidalgo
Jun 15, 2006·The Journal of Physical Chemistry. B·Gregory J WilsonRichard D Webster
Jul 20, 2006·Journal of Agricultural and Food Chemistry·Francisco J HidalgoRosario Zamora
May 10, 2007·Journal of Agricultural and Food Chemistry·Francisco J HidalgoRosario Zamora
Sep 28, 2007·Journal of Oleo Science·Atsushi TakenakaKazuo Miyashita
Oct 23, 2010·Journal of Agricultural and Food Chemistry·Bingcan ChenEric Andrew Decker
Jul 31, 2013·Journal of Agricultural and Food Chemistry·Junki ShimajiriKazuo Miyashita

❮ Previous
Next ❯

Citations

Jun 26, 2015·Journal of the Science of Food and Agriculture·Leqi Cui, Eric A Decker
Jun 15, 2016·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·L SagalowiczM Michel
Jan 13, 2018·Annual Review of Food Science and Technology·Kazuo MiyashitaMasashi Hosokawa
May 15, 2020·Science Translational Medicine·Xiaowen YuAihua Zhang
Jan 23, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jana GoritschnigMarc Pignitter
Dec 14, 2018·Journal of Oleo Science·Miyashita Kazuo
Apr 10, 2018·Journal of Agricultural and Food Chemistry·Gautam K SamdaniEric A Decker
Jun 15, 2019·Journal of Agricultural and Food Chemistry·Na XuEric A Decker
May 28, 2019·Journal of Agricultural and Food Chemistry·Andrea BaschieriLuca Valgimigli

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.