Impact of pre-procedural serum albumin levels on outcome of patients undergoing transcatheter aortic valve replacement

The American Journal of Cardiology
Edward KoifmanRon Waksman

Abstract

Risk assessment for transcatheter aortic valve replacement (TAVR) patients is challenging, and surgical scores do not optimally correlate with outcome. The aim of this study was to assess the correlation between serum albumin and survival of patients with symptomatic severe aortic stenosis undergoing TAVR. Patients with severe aortic stenosis who underwent TAVR were categorized into 2 groups according to low and normal preprocedural serum albumin (<3.5 and ≥3.5 g/dl, respectively). The all-cause mortality rates at hospital discharge, at 30-day and 1-year follow-up were compared across the groups. Additionally, a Cox proportional-hazards model was generated to assess the independent effect of serum albumin at 1-year follow-up. Among 567 consecutive patients who underwent TAVR, 476 (84%) had documented preprocedural serum albumin measurements. Of these, 50% had low serum albumin levels, and 50% had normal serum albumin levels. Baseline and procedural characteristics, including age, gender, and transapical access, were similar among the groups. Prevalence of left ventricular ejection fraction<40% was higher in patients with low albumin (29% vs 20%, p=0.02), and risk assessment according to Society of Thoracic Surgeons score tended...Continue Reading

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Citations

Mar 18, 2017·Circulation·Tetsuro ShimuraUNKNOWN OCEAN-TAVI Investigators
Jul 31, 2020·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Masanori YamamotoKentaro Hayashida
Mar 9, 2019·Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery·Aravind KrishnanKaushik Mandal
May 13, 2020·Journal of Cardiothoracic Surgery·David Berbel-FrancoGiovanni Landoni
Mar 20, 2020·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·M S van MourikM M Vis
Jan 25, 2020·JACC. Cardiovascular Interventions·Soroosh KianiUNKNOWN STS/ACC TVT Registry
May 10, 2020·JACC. Cardiovascular Interventions·Melissa BendayanJonathan Afilalo

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