Impact of predischarge nocturnal pulse oximetry (sleep-disordered breathing) on postdischarge clinical outcomes in hospitalized patients with left ventricular systolic dysfunction after acute decompensated heart failure

The American Journal of Cardiology
Takayasu OhmuraHiroyuki Daida

Abstract

Stratifying patients at a high risk for readmission and mortality before their discharge after acute decompensated heart failure (ADHF) is important. Although sleep-disordered breathing (SDB) is prevalent in patients with chronic heart failure, only few studies have investigated the impact of SDB on hospitalized patients with left ventricular (LV) systolic dysfunction after ADHF. Thus, we assessed the prevalence of SDB using nocturnal pulse oximetry and the relation between SDB and clinical events in this patient group. One hundred consecutive patients with LV systolic dysfunction who were hospitalized for ADHF were enrolled in the study. Predischarge nocturnal oximetry was performed to determine if they had SDB (defined as an oxygen desaturation index of ≥5 events/hour with ≥4% decrease in saturation level). Data on death and readmission for ADHF were collected. Forty-one patients had SDB. Complete outcome data were collected in the mean follow-up period of 14.2 months during which 33 events occurred. On multivariate Cox proportional hazards regression analysis, the presence of SDB was a significant independent predictor of postdischarge readmission and mortality (hazard ratio 2.93, p = 0.006). In conclusion, SDB, as determine...Continue Reading

References

Dec 23, 1971·The New England Journal of Medicine·P A McKeeW B Kannel
Oct 7, 1998·Journal of Applied Physiology·J YuE C Fletcher
Feb 27, 2003·Circulation Journal : Official Journal of the Japanese Circulation Society·Haruo MitaniShunnichi Fukuhara
May 26, 2005·Circulation Journal : Official Journal of the Japanese Circulation Society·Kentaro MeguroRyozo Nagai
Dec 27, 2005·Circulation Journal : Official Journal of the Japanese Circulation Society·Shigetake SasayamaUNKNOWN CHF-HOT Study Group
Aug 17, 2006·Journal of Sleep Research·R TkacovaT D Bradley
Apr 17, 2007·Journal of the American College of Cardiology·Hanqiao WangT Douglas Bradley
Aug 19, 2007·Chest·Caterina B BuccaAlessandro Cicolin
Jan 6, 2009·Circulation Journal : Official Journal of the Japanese Circulation Society·Akira TamuraJunichi Kadota
Apr 3, 2009·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Seiichi MatsuoUNKNOWN Collaborators developing the Japanese equation for estimated GFR
Apr 21, 2009·Archives of Cardiovascular Diseases·Alexandra PaulinoMarie-Pia d'Ortho
Mar 2, 2010·The European Respiratory Journal·C M RyanUNKNOWN CANPAP Investigators
Nov 10, 2011·Sleep & Breathing = Schlaf & Atmung·Ozcan OzekeAhmet Duran Demir
Jul 25, 2012·Journal of cardiology·Takatoshi Kasai
Sep 19, 2012·Circulation·Takatoshi KasaiT Douglas Bradley
Aug 16, 2016·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Gilli ErezFliss E M Murtagh

❮ Previous
Next ❯

Citations

Sep 15, 2015·European Journal of Clinical Investigation·Michele CorrealeDonato Lacedonia
Jun 27, 2015·The Canadian Journal of Cardiology·Yanru LiAtul Malhotra
Jun 27, 2015·The Canadian Journal of Cardiology·Frédéric Sériès
May 14, 2016·Nature Reviews. Cardiology·Gianfranco ParatiUNKNOWN Italian Society of Cardiology (SIC) Working Group on Heart Failure members
Oct 21, 2016·Current Heart Failure Reports·Martin R Cowie
Apr 11, 2018·Der Internist·H WoehrleM Arzt
Jun 11, 2019·Journal of Sleep Research·Nuria Toledo-PonsFrancisco García-Río
Apr 9, 2020·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Bilal SamhouriNeal F Chaisson
Apr 2, 2018·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Shoichiro YatsuHiroyuki Daida
May 21, 2021·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Shoichiro YatsuHiroyuki Daida

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Cardiovascular Diseases: Risk Factors

Cardiovascular disease is a significant health concern. Risk factors include hypertension, obesity, dyslipidemia and smoking. Women who are postmenopausal are at an increased risk of heart disease. Here is the latest research for risk factors of cardiovascular disease.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.