Impact of premorbid undernutrition on outcome in stroke patients

Stroke; a Journal of Cerebral Circulation
James P DavisStephen J Read

Abstract

To assess the prevalence of premorbid undernutrition and its impact on outcomes 1 month after stroke. The study recruited from consecutive stroke admissions during a 10-month period. Premorbid nutritional status (using the subjective global assessment [SGA]), premorbid functioning (modified Rankin scale [MRS]), and stroke severity (National Institutes of Health Stroke Scale [NIHSS] score) were assessed at admission. The associations between premorbid nutritional status, poor outcome (defined as MRS > or =3), and mortality were examined before and after adjustment for confounding variables, including age, gender, stroke risk factors, stroke severity, and admission serum albumin. Thirty of 185 patients were assessed as having undernutrition at admission. Significant unadjusted associations were observed between undernutrition and poor outcome (odds ratio [OR], 3.4; 95% CI, 1.3 to 8.7; P=0.01), and mortality (OR, 3.1, 95% CI, 1.3 to 7.7; P=0.02) at 1 month. NIHSS, age, and premorbid MRS were also significantly associated with poor outcomes. After adjustment for these factors, the effect size of associations remained important but not significant (poor outcome: OR, 2.4; 95% CI, 0.7 to 9.0, P=0.18; mortality: OR, 3.2; 95% CI, 1.0 to...Continue Reading

References

Jun 1, 1989·Archives of Neurology·L B GoldsteinJ N Davis
Jan 1, 1988·Acta Medica Scandinavica·K AxelssonI Alafuzoff
Sep 1, 1987·JPEN. Journal of Parenteral and Enteral Nutrition·A S DetskyK N Jeejeebhoy
Jan 1, 1987·JPEN. Journal of Parenteral and Enteral Nutrition·A S DetskyK N Jeejeebhoy
Jul 1, 1985·Journal of Gerontology·M A DavisS Margen
Mar 1, 1984·JPEN. Journal of Parenteral and Enteral Nutrition·A S DetskyK N Jeejeebhoy
Apr 22, 1982·The New England Journal of Medicine·J P BakerK N Jeejeebhoy
Jan 1, 1982·Acta Medica Scandinavica·N AlbiinL Bjermer
Apr 1, 1995·Archives of Physical Medicine and Rehabilitation·H M FinestoneR W Teasell
Apr 9, 1994·BMJ : British Medical Journal·J P McWhirter, C R Pennington
Apr 1, 1996·Archives of Physical Medicine and Rehabilitation·H M FinestoneR W Teasell
Oct 23, 1997·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·R KothariJ Broderick
Feb 28, 1998·The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses·J SpilkerS Sailor
Aug 13, 1998·The American Journal of Clinical Nutrition·S E GariballaC M Castleden
Feb 15, 2001·Neuroepidemiology·S M Lai, P W Duncan
Aug 16, 2002·Clinical Nursing Research·Neva L CroganRobert A Short
Feb 15, 2003·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Catherine PaquetLaurette Dubé
May 17, 2003·Stroke; a Journal of Cerebral Circulation·UNKNOWN FOOD Trial Collaboration
Jun 7, 2003·Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society·Joyce K Stechmiller

❮ Previous
Next ❯

Citations

Nov 18, 2008·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Yoon-Mi ChoSam-Gyu Lee
Nov 17, 2010·Neurocritical Care·Adnan I Qureshi
Feb 28, 2013·European Journal of Clinical Nutrition·H Lim, R Choue
Jan 26, 2007·European Journal of Clinical Nutrition·T DziedzicA Szczudlik
Apr 12, 2006·Current Opinion in Clinical Nutrition and Metabolic Care·M Cristina G Barbosa-Silva, Aluísio J D Barros
Jun 10, 2010·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·K ShibazakiK Kobayashi
Jul 17, 2013·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Shari E SmithPhyllis G Paterson
Nov 21, 2012·Disability and Rehabilitation·Marianne E KlinkeHelga Jónsdóttir
Jan 25, 2014·Brain Injury : [BI]·Roberto AquilaniFederica Boschi
Jan 23, 2016·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Filomena GomesC Elizabeth Weekes
Oct 30, 2015·Circulation Journal : Official Journal of the Japanese Circulation Society·Tomohisa NezuUNKNOWN Japan Standard Stroke Registry Study Group
Aug 31, 2010·Archives of Gerontology and Geriatrics·Hsiu-Chu ShenShinn-Jang Hwang
Sep 28, 2015·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Maria NiiAtsuko Tanaka
Feb 24, 2010·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Lisa HaPer Ole Iversen
Apr 17, 2007·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·P Claire LangdonColin W Binns
Mar 19, 2016·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Yoji KokuraSotaro Higashi
May 25, 2011·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·W F R NipA Mackenzie
Oct 2, 2007·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Michael A CraryScott Silliman
Apr 26, 2005·Lancet Neurology·Robert Teasell, Norine Foley
Apr 1, 2014·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Julie PaquereauMarc Rousseaux
Sep 17, 2014·Journal of Cachexia, Sarcopenia and Muscle·Hidetaka Wakabayashi, Kunihiro Sakuma
Dec 21, 2012·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Baidarbhi ChakrabortySarita Agarwal
Jan 17, 2012·Atherosclerosis·Tomasz DziedzicAgnieszka Slowik
Jul 26, 2014·Journal of Korean Academy of Nursing·Sung Hee Yoo, So Sun Kim
Aug 21, 2016·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Akie NakadateMeigen Liu
Aug 30, 2016·Disability and Rehabilitation·Rebecca Shisler Marshall, Bijoyaa Mohapatra
May 19, 2011·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Mandy L CorriganDonald F Kirby
Feb 6, 2018·Translational Stroke Research·Mariam AlaverdashviliPhyllis G Paterson
Sep 27, 2018·Journal of the American College of Nutrition·Fereshteh AliasghariReza Deljavan
May 3, 2014·Stroke; a Journal of Cerebral Circulation·Walter N KernanUNKNOWN American Heart Association Stroke Council, Council on Cardiovascular and Stroke Nursing, Council on Clinical Cardiology, and
Apr 21, 2007·Stroke; a Journal of Cerebral Circulation·Angela M CarterPeter J Grant
Jan 24, 2009·Stroke; a Journal of Cerebral Circulation·Norine C FoleyM Gail Woodbury
Aug 12, 2017·Neurocritical Care·Toni Sabbouh, Michel T Torbey
Jan 23, 2019·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·C PorterM Palmer

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.