Impact of Preoperative Anemia on Perioperative Outcomes in Patients Undergoing Elective Colorectal Surgery

Gastroenterology Research and Practice
Liu LiuQiang Huang

Abstract

To evaluate the impact of preoperative anemia (POA) on perioperative outcomes in patients undergoing elective surgery for colorectal cancer (CRC). A total of 326 CRC patients were enrolled. POA was defined as a hemoglobin (Hb) concentration ≤ 12 g/dl. Univariable and multivariable analyses were performed to assess the impact of POA on the risks of postoperative complications like surgical site infection (SSI). Patients with colon cancer presented higher rate of POA than patients with rectal cancer (60% versus 40% for colon cancer versus rectal cancer). In addition, female patients and patients with large tumor mass (>4 cm) had a higher rate of POA than male patients and patients with small tumor (≤4 cm), respectively. Upon univariable analysis, CRC patients with POA had a higher rate of incisional SSI than patients without POA (12% versus 6%, P = 0.04). However, POA was not associated with other postoperative complications, like anastomotic leak, organ space SSI, and bleeding. Upon multivariable analysis, POA and stoma formation were identified as two independent risk factors for incisional SSI (OR (95%CI): 2.44 (1.09-5.49) for POA versus no POA and 2.64 (1.20-5.81) for stoma formation versus no stoma formation). POA was an ind...Continue Reading

References

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Citations

Feb 23, 2020·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Nicolò TaminiLuca Nespoli

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Methods Mentioned

BETA
dissection
coronary artery bypass

Software Mentioned

SPSS
SPSS®

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