Abstract
To evaluate the impact of preoperative anemia (POA) on perioperative outcomes in patients undergoing elective surgery for colorectal cancer (CRC). A total of 326 CRC patients were enrolled. POA was defined as a hemoglobin (Hb) concentration ≤ 12 g/dl. Univariable and multivariable analyses were performed to assess the impact of POA on the risks of postoperative complications like surgical site infection (SSI). Patients with colon cancer presented higher rate of POA than patients with rectal cancer (60% versus 40% for colon cancer versus rectal cancer). In addition, female patients and patients with large tumor mass (>4 cm) had a higher rate of POA than male patients and patients with small tumor (≤4 cm), respectively. Upon univariable analysis, CRC patients with POA had a higher rate of incisional SSI than patients without POA (12% versus 6%, P = 0.04). However, POA was not associated with other postoperative complications, like anastomotic leak, organ space SSI, and bleeding. Upon multivariable analysis, POA and stoma formation were identified as two independent risk factors for incisional SSI (OR (95%CI): 2.44 (1.09-5.49) for POA versus no POA and 2.64 (1.20-5.81) for stoma formation versus no stoma formation). POA was an ind...Continue Reading
References
Oct 6, 1998·Archives of Internal Medicine
Mar 19, 2002·World Journal of Surgery·Ludger StaibHans Günther Beger
Mar 31, 2004·The American Journal of Medicine·Kevin KnightLodovico Balducci
Apr 15, 2004·Annals of Surgery·Robert L SmithEugene F Foley
Mar 16, 2006·European Heart Journal·Mercè CladellasMiquel Gomez
Jul 6, 2007·World Journal of Surgical Oncology·Bruno AndreoniLorenzo Monfardini
Dec 4, 2008·The Annals of Thoracic Surgery·Melanie L BellA Laurie W Shroyer
Sep 3, 2010·Anesthesiology·Min LiThomas F Floyd
May 18, 2011·Archives of Surgery·Elizabeth C WickMartin A Makary
Jun 22, 2011·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·K H KimJ C Kim
Jul 10, 2012·Clinical Orthopaedics and Related Research·Max GreenkyJavad Parvizi
Sep 26, 2012·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Do-Hyun JungHan-Kwang Yang
May 31, 2013·Perfusion·P J DarbyC D Mazer
May 16, 2014·British Journal of Anaesthesia·D M BaronUNKNOWN European Society of Anaesthesiology
Feb 15, 2015·The Spine Journal : Official Journal of the North American Spine Society·Stein J JanssenJoseph H Schwab
Aug 11, 2015·Annals of Surgery·Ravi Pokala KiranKenneth Forde
Sep 6, 2015·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·W A A BorstlapW A Bemelman
Sep 10, 2015·The British Journal of Surgery·A J FowlerR M Pearse
Oct 29, 2015·International Journal of Colorectal Disease·Derek B HennesseyKenneth Mealy
Feb 26, 2016·Annals of Medicine and Surgery·Barrie D KeelerAustin G Acheson