Impact of recommendations on crushing medications in geriatrics: from prescription to administration

Fundamental & Clinical Pharmacology
Gwladys BourdenetJean Doucet

Abstract

The practice of crushing drugs is very common in geriatric units. In 2009 a first study, performed in all geriatric units of a university hospital, showed that numerous errors were made during prescription, preparation and administration. The aim of this second prospective study was to assess the impact of regional and national recommendations in the same geriatric units. A survey of 719 patients (85.3 ± 6.7 years) was performed in 2013. For each patient who received crushed drugs, we recorded the reason the drugs were crushed, pharmacological classes, galenic presentations and the technique used for preparation and administration. Results were compared to the previous study. The number of patients receiving drugs after crushing was significantly lower than in the previous study (22.9% vs. 32.3%, P < 0.001). The number of crushed drugs was lower too (594 per 165 patients vs. 966 per 224 patients (P < 0.01). The main indication for crushing drugs remained swallowing disorders. The dosage form prevented crushing in 24.9% of drugs (vs. 42.0% in 2009, P < 0.001), but the drugs generally remained crushed all together. A mortar was used less often (38.6% vs. 92.6%, P < 0.001), with preference for individual-specific cups (56.1%). Mor...Continue Reading

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Citations

Nov 12, 2015·Fundamental & Clinical Pharmacology·Fanny EtchepareMarie Tournier
Jun 28, 2016·International Journal of Pharmaceutics·Aoife Mc GillicuddyLaura J Sahm
Mar 2, 2018·PloS One·Min Yew ThongKathryn J Steadman
Oct 4, 2017·The Journal of Nutrition, Health & Aging·M FodilC Trivalle
Jan 1, 2017·European Journal of Hospital Pharmacy. Science and Practice·Corina Naughton, Nicky Hayes
Aug 6, 2020·Pharmacy : Journal of Pharmacy, Education and Practice·Soraya QassemiPhilippe Cestac
Oct 20, 2020·International Journal of Antimicrobial Agents·Guillaume BinsonAntoine Dupuis
Feb 10, 2021·Geriatric Nursing·Hege SolbergRose Mari Olsen
Sep 26, 2020·Journal of Pain and Symptom Management·Amanda G LovellMaureen L Saphire
Nov 24, 2020·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·David NguyenJoël Schlatter

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