Impact of stroke-associated pneumonia on mortality, length of hospitalization, and functional outcome

Acta Neurologica Scandinavica
W H TehPhyo Kyaw Myint

Abstract

Stroke-associated pneumonia (SAP) is common and associated with adverse outcomes. Data on its impact beyond 1 year are scarce. This observational study was conducted in a cohort of stroke patients admitted consecutively to a tertiary referral center in the east of England, UK (January 2003-April 2015). Logistic regression models examined inpatient mortality and length of stay (LOS). Cox regression models examined longer-term mortality at predefined time periods (0-90 days, 90 days-1 year, 1-3 years, and 3-10 years) for SAP. Effect of SAP on functional outcome at discharge was assessed using logistic regression. A total of 9238 patients (mean age [±SD] 77.61 ± 11.88 years) were included. SAP was diagnosed in 1083 (11.7%) patients. The majority of these cases (n = 658; 60.8%) were aspiration pneumonia. After controlling for age, sex, stroke type, Oxfordshire Community Stroke Project (OCSP) classification, prestroke modified Rankin scale, comorbidities, and acute illness markers, mortality estimates remained significant at 3 time periods: inpatient (OR 5.87, 95%CI [4.97-6.93]), 0-90 days (2.17 [1.97-2.40]), and 91-365 days (HR 1.31 [1.03-1.67]). SAP was also associated with higher odds of long LOS (OR 1.93 [1.67-2.22]) and worse f...Continue Reading

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Citations

Oct 10, 2018·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·M LopesC Ferreira
May 1, 2019·Acta neurologica Belgica·Rory J TinkerPhyo K Myint
May 7, 2020·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·X LiJ Zou
Feb 21, 2021·Asthma Research and Practice·A CorlateanuN Siafakas
Jan 3, 2021·The American Journal of Emergency Medicine·Quanpeng WangJun Wang
Feb 27, 2021·Journal of the American Heart Association·Júlia FauraJoan Montaner
Apr 20, 2021·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Amit K KishoreCraig J Smith
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Apr 21, 2021·Neurology·Dominik LehriederUNKNOWN DESTINY-R (Decompressive Surgery for the Treatment of Malignant Infarction of the Middle Cerebral Artery Registry) Study Gro
Jun 8, 2021·Neuropsychiatric Disease and Treatment·Wei ChengJian Chen
Sep 17, 2021·BMC Nursing·Munirah BangeeElizabeth Lightbody
Sep 30, 2021·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·João C Gonçalves-PereiraFilipe Froes

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