Impact of telephonic psycho-social support on adherence to post-exposure prophylaxis (PEP) after rape

AIDS Care
Naeemah AbrahamsBanwari Meel

Abstract

South Africa has one of the highest rates of both rape and HIV infections. Of great concern is the possibility of HIV transmission during the assault, but adherence to post-exposure prophylaxis (PEP) has been varied and low. We developed a telephonic psycho-social support, leaflet and adherence diary intervention for rape victims and tested its impact on adherence to PEP. A randomised control trial was conducted in the Western and Eastern Cape and 279 rape survivors were enrolled in two arms. The intervention involved the providing of an information leaflet including an adherence diary and follow-up support through telephone calls by a counsellor during the 28 days of taking the PEP. The controls received the leaflet. Follow-up interviews and tablet checks were done with 253 participants to assess adherence. The primary outcome was completion of 28 days of PEP with no more than three missed doses (94% adherence). There was more adherence in the intervention arm (38.2% vs. 31.9%), but the estimated intervention effect of 6.5% (95% CI: -4.6 to 17.6%) was not statistically significant, p=0.13. The intervention was associated with the reading of the pamphlet (p=0.07) and an increased use of the diary (p=0.01), but did not reduce de...Continue Reading

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Citations

Jan 15, 2014·Global Advances in Health and Medicine : Improving Healthcare Outcomes Worldwide·Bridgette M BrawnerLoretta Sweet Jemmott
Apr 12, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Isaac I BogochJason R Andrews
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Apr 1, 2015·AIDS Patient Care and STDs·Lawrence MbuagbawUNKNOWN Patient Adherence Review (PAR) Team
Mar 3, 2015·Journal of the American Medical Informatics Association : JAMIA·Niraj MistryUNKNOWN Patient Adherence Review Team
Apr 13, 2018·Health Care for Women International·Michelle E DemingXiaoming Li
Jun 4, 2013·The Cochrane Database of Systematic Reviews·Michelle H M M T van-VelthovenJosip Car
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Oct 5, 2018·Journal of General Internal Medicine·Karen M GoldsteinJennifer M Gierisch
Aug 3, 2021·AIDS Care·Briana OrtegaDiane M Straub

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