Impact of the Gastro-Intestinal Bacterial Microbiome on Helicobacter -Associated Diseases

Healthcare
Maxime Pichon, Christophe Burucoa

Abstract

Helicobacter pylori is a bacterium that selectively infects the gastric epithelium of half of the world population. The microbiome, community of microorganisms gained major interest over the last years, due to its modification associated to health and disease states. Even if most of these descriptions have focused on chronic disorders, this review describes the impact of the intestinal bacterial microbiome on host response to Helicobacter associated diseases. Microbiome has a direct impact on host cells, major barrier of the gastro-intestinal tract, but also an indirect impact on immune system stimulation, by enhancing or decreasing non-specific or adaptive response. In microbial infections, especially in precancerous lesions induced by Helicobacter pylori infection, these modifications could lead to different outcome. Associated to data focusing on the microbiome, transcriptomic analyses of the eukaryote response would lead to a complete understanding of these complex interactions and will allow to characterize innovative biomarkers and personalized therapies.

References

Nov 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·C R Woese, G E Fox
Feb 13, 2001·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·I AdamssonC E Nord
Dec 11, 2002·Best Practice & Research. Clinical Gastroenterology·Fergus Shanahan
Jan 13, 2006·Proceedings of the National Academy of Sciences of the United States of America·Elisabeth M BikDavid A Relman
Jul 5, 2006·EMBO Reports·Ann M O'Hara, Fergus Shanahan
Oct 3, 2006·Inflammatory Bowel Diseases·Antonio Tursi
Mar 6, 2007·Clinics·Bruno ZilbersteinJoaquim Gama-Rodrigues
May 21, 2009·FEMS Immunology and Medical Microbiology·Leif Percival Andersen, Lone Rasmussen
Sep 5, 2009·The Journal of Clinical Investigation·John C Atherton, Martin J Blaser
Apr 13, 2010·Nature Methods·J Gregory CaporasoRob Knight
Jul 29, 2010·Physiological Reviews·Inna SekirovB Brett Finlay
Oct 12, 2010·The ISME Journal·Ana Maldonado-ContrerasMaria G Dominguez-Bello
Mar 3, 2011·PloS One·John R Erb-DownwardGary B Huffnagle
Jul 12, 2011·The Journal of Infectious Diseases·Ronit Cohen-PoradosuDennis L Kasper
Nov 18, 2011·Trends in Microbiology·Nathalie Juge
Dec 27, 2011·The American Journal of the Medical Sciences·Ji-Wei ZhangChun-Mei Ying
Jun 22, 2012·PloS One·Susan M HuseAnthony A Fodor
Feb 26, 2013·Nature Reviews. Microbiology·Felix Sommer, Fredrik Bäckhed
May 22, 2013·Proceedings of the National Academy of Sciences of the United States of America·Jeremy J BarrForest Rohwer
Jun 19, 2013·Best Practice & Research. Clinical Gastroenterology·Lars Engstrand, Mathilda Lindberg
Apr 16, 2014·Frontiers in Cellular and Infection Microbiology·Marianne De PaepeMarie-Agnès Petit
Apr 29, 2014·Molecular Cell·Thergiory IrrazábalDana J Philpott
May 24, 2014·The Cancer Journal·Kyle M BrawnerPhillip D Smith
Jun 13, 2014·Gut Microbes·Markus B GeukingKathy D McCoy
Sep 12, 2014·PLoS Genetics·Philipp EngelNancy A Moran
Mar 13, 2015·Current Gastroenterology Reports·Emanuelle Bellaguarda, Eugene B Chang
Jul 17, 2015·JAMA Oncology·Kosuke MimaShuji Ogino
Sep 9, 2015·Future Microbiology·Zhao-Fei ChenJing-Yuan Fang
Sep 16, 2015·Helicobacter·Dionyssios N SgourasYoshio Yamaoka
Nov 3, 2015·World Journal of Gastroenterology : WJG·Yao-Kuang WangDeng-Chyang Wu
May 24, 2016·The Turkish Journal of Gastroenterology : the Official Journal of Turkish Society of Gastroenterology·Sufang LiangZhenjun Wu
Jul 28, 2016·Frontiers in Microbiology·Jessica D ForbesCharles N Bernstein

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Citations

Oct 24, 2019·Annals of the New York Academy of Sciences·Apostolis PapaefthymiouJannis Kountouras
May 14, 2020·PLoS Neglected Tropical Diseases·Sivaranjani NamasivayamMamoudou Maiga
Jan 4, 2020·Therapeutic Advances in Gastroenterology·Christian SchulzPeter Malfertheiner
Aug 26, 2021·Annals of Medicine·Haiqing LiangGuifang Zheng

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Methods Mentioned

BETA
biopsies
glycosylation

Software Mentioned

UPARSE
QIIME2
mother

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