Impact of the introduction of EBUS on time to management decision, complications, and invasive modalities used to diagnose and stage lung cancer: a pragmatic pre-post study

BMC Cancer
Neli S Slavova-AzmanovaMartin Phillips

Abstract

Utilisation of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) and guide sheath (EBUS-GS) for diagnosis and staging of lung cancer is gaining popularity, however, its impact on clinical practice is unclear. This study aimed to determine the impact of the introduction of endobronchial ultrasound-guided procedures (EBUS) on time to management decision for lung cancer patients, and on the utilisation of other invasive diagnostic modalities, including CT-guided trans-thoracic needle aspiration (CT-TTNA), bronchoscopy, and mediastinoscopy. Hospital records of new primary lung cancer patients presenting in 2007 and 2008 (Pre-EBUS cohort) and in 2010 and 2011 (Post-EBUS cohort) were reviewed retrospectively. The Pre-EBUS cohort included 234 patients. Of the 326 patients in the Post-EBUS cohort, 90 had an EBUS procedure (EBUS-TBNA for 19.0% and EBUS-GS for 10.4% of cases). The number of CT-TTNAs and bronchoscopies decreased following the introduction of EBUS (p = 0.015 and p < 0.001 respectively). Of 162 CT-TTNAs, 59 (36%) resulted in complications compared to 1 complication each for bronchoscopy and EBUS-GS, and no complications from EBUS-TBNA. Fewer complications occurred overall in the Post-EBUS cohort c...Continue Reading

References

Dec 1, 1982·American Journal of Clinical Oncology·M M OkenP P Carbone
Mar 16, 2005·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Daniel R BrooksSteven D Stellman
Nov 25, 2005·The Annals of Thoracic Surgery·Alex G LittleAndrew K Stewart
Oct 6, 2007·Chest·Gerard A SilvestriUNKNOWN American College of Chest Physicians
Aug 12, 2009·Journal of Pain & Palliative Care Pharmacotherapy·UNKNOWN National Institute of Neurological Disorders, National Institutes of Health
Nov 26, 2010·JAMA : the Journal of the American Medical Association·Jouke T AnnemaKurt G Tournoy
Jan 22, 2011·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·George R Simon, Gerard A Silvestri
Jan 22, 2011·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·William D TravisDavid Yankelewitz
Aug 2, 2011·Respirology : Official Journal of the Asian Pacific Society of Respirology·Rocco TrisoliniMarco Patelli
Apr 14, 2012·Clinical Lung Cancer·Jos A StigtHarry J M Groen
Jun 2, 2012·American Journal of Respiratory and Critical Care Medicine·Neal NavaniUNKNOWN REMEDY Trial Investigators
Jun 12, 2013·General Thoracic and Cardiovascular Surgery·Yuichi SakairiIchiro Yoshino
Nov 22, 2013·QJM : Monthly Journal of the Association of Physicians·R J JoséN Navani

❮ Previous
Next ❯

Citations

Jan 10, 2018·International Journal of Clinical Practice·Fotios SampsonasKonstantinos Spiropoulos
Mar 15, 2019·Asia-Pacific Journal of Clinical Oncology·Phillip ParenteEmily Stone
Feb 6, 2017·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Sahar MokhlesJohanna J M Takkenberg

❮ Previous
Next ❯

Methods Mentioned

BETA
sedation
surgical resection

Software Mentioned

STATA
SPSS

Related Concepts

Related Feeds

Adenomatous Polyposis Coli

Adenomatous polyposis coli is a protein encoded by the APC gene and acts as a tumor suppressor. Discover the latest research on adenomatous polyposis coli here.

© 2021 Meta ULC. All rights reserved