Impact of the severity of hypoglycemia on health - Related quality of life, productivity, resource use, and costs among US patients with type 2 diabetes

Journal of Diabetes and Its Complications
Manjiri PawaskarSwapnil Rajpathak

Abstract

To explore the association between hypoglycemia severity and health-related quality of life (HRQoL), productivity, health care resource utilization (HCRU), and costs among patients with type 2 diabetes mellitus (T2DM). Data were from the 2013 US National Health and Wellness Survey. This analysis included adults with treated T2DM. Participants were categorized based upon their self-reported experience in the previous 3 months: no hypoglycemia, non-severe hypoglycemia, or severe hypoglycemia. Validated instruments were used to measure HRQoL and productivity; HCRU was based on participant-reported health care provider (HCP) and emergency department (ED) visits and hospitalizations. Multivariable models tested for trends across the severity groups. The analysis included 3630 participants-1729 (47.6%) with non-severe hypoglycemia and 172 (4.7%) with severe hypoglycemia. Mental and physical component scores and utility scores were significantly associated with hypoglycemia severity (P < 0.001 for each). Similar trends were observed for absenteeism (P < 0.001), presenteeism (P = 0.005), HCP and ED visits (P ≤ 0.002), and hospitalizations (P < 0.001). Annual HCRU costs associated with increasingly severe hypoglycemia were $6908, $7132,...Continue Reading

Citations

Sep 11, 2020·Journal of Clinical Pharmacy and Therapeutics·Andrew Bzowyckyj
Mar 28, 2019·Clinics·Helga Dos Santos CabeceiraDaniela Francescato Veiga
Jan 31, 2019·Journal of Occupational Health·Koji MoriNatsumi Shinzato
Feb 18, 2021·Medicine·Kuixu LanJunfang Xu
Mar 2, 2021·Journal of Managed Care & Specialty Pharmacy·Sanjay BajpaiChanadda Chinthammit
Apr 11, 2021·Journal of Diabetes and Its Complications·Lizheng ShiBelinda Childs
Jul 22, 2021·Journal of Comparative Effectiveness Research·Xuanqian XieAndrei Volodin
Feb 9, 2021·Clinical Diabetes : a Publication of the American Diabetes Association·Clifford J Bailey, James R Gavin

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