Impact of Total Laboratory Automation on Turnaround Times for Urine Cultures and Screening Specimens for MRSA, ESBL, and VRE Carriage: Retrospective Comparison With Manual Workflow.

Frontiers in Cellular and Infection Microbiology
Abdessalam CherkaouiJacques Schrenzel

Abstract

Using computerized time-stamps, we compared the turnaround-times (TAT) for urine samples and screening ESwabs of MRSA, VRE, and ESBL carriage in the bacteriology laboratory of Geneva University Hospitals between January and December 2017 (period preceding the implementation of the WASPLabTM) with the same specimen types analyzed between January and December 2019 (period after the implementation of the automation). During both 1-year periods, a total of 98'380 specimens were analyzed (48'158 in 2017 vs. 50'222 in 2019). On the WASPLabTM, all culture plates were imaged at defined intervals each day of incubation, but the processing of the cultures (i.e., pathogen identification and antimicrobial susceptibility testing) was only performed during day shift hours (~8:00 A.M. to 4:30 P.M.). The median TAT for negative reports decreased by almost half for urine samples from 52.1 (2017) to 28.3 h (2019) (p < 0.001), and for MRSA screening specimens from 50.7 to 26.3 h (p < 0.001). The difference in median TAT for negative reports was less pronounced for screening of ESBL (50.2 vs. 43.0 h) (p < 0.001) and VRE (50.6 vs. 45.7 h) (p < 0.001). Despite a trend toward shorter result delivery for positive samples, there was no significant chan...Continue Reading

References

Apr 13, 2007·Journal of Clinical Microbiology·Patrice FrancoisJacques Schrenzel
Jun 1, 2012·Critical Care : the Official Journal of the Critical Care Forum·Arash AfshariStephan Harbarth
Nov 19, 2015·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·Olivier DauwalderGerard Lina
Jun 27, 2018·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Irene BurckhardtStefan Zimmermann
Oct 1, 2018·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Melanie L YarbroughCarey-Ann D Burnham
Jan 25, 2019·Antimicrobial Resistance and Infection Control·Niccolò BuettiUNKNOWN for Swissnoso
Apr 16, 2019·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·A CherkaouiJ Schrenzel
Nov 30, 2019·Frontiers in Cellular and Infection Microbiology·Abdessalam CherkaouiJacques Schrenzel
Jan 23, 2020·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Abdessalam CherkaouiJacques Schrenzel
Apr 6, 2020·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Abdessalam CherkaouiJacques Schrenzel

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Software Mentioned

WASPLab
RStudio
R
WASPLab TM
Unilab2

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