Impact of treatment for bacterial vaginosis on prematurity among Brazilian pregnant women: a retrospective cohort study

São Paulo Medical Journal = Revista Paulista De Medicina
Rodrigo P S CamargoSebastian Faro

Abstract

Bacterial vaginosis has been associated with prematurity and other perinatal complications. However, the efficacy of the treatment for preventing such complications has not yet been well established. The objective of this study was to evaluate the impact of treatment for bacterial vaginosis on a low-risk population of Brazilian pregnant women, in order to prevent prematurity and other perinatal complications. Observational retrospective cohort study, at the Obstetric and Gynecology Department, Universidade Estadual de Campinas (Unicamp). Vaginal bacterioscopy results from 785 low-risk pregnant women were studied. Three different groups of women were identified: 580 without bacterial vaginosis during pregnancy, 134 with bacterial vaginosis treated using imidazoles (metronidazole, tinidazole, or secnidazole) during pregnancy, and 71 with bacterial vaginosis not treated during pregnancy. The diagnosis of bacterial vaginosis was based on Nugent's criteria, from the vaginal bacterioscopy performed during the first prenatal care visit. The frequency of prematurity was 5.5% among the women without bacterial vaginosis, 22.5% among those with untreated bacterial vaginosis and 3.7% among those with treated bacterial vaginosis. The risk r...Continue Reading

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Citations

Jan 13, 2018·Future Microbiology·Paul Nyirjesy, Jane R Schwebke
Dec 24, 2005·Current Opinion in Infectious Diseases·Gilbert G G Donders
Apr 25, 2013·Current Opinion in Infectious Diseases·Marianne CunningtonPaul Heath

Related Concepts

Imidazoles
Premature Obstetric Labor
Pregnancy Complications, Infectious
Pregnancy Outcome
Retrospective Studies
Incidence Studies
Logistic Regression
Bacterial Vaginosis

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