Impact of various iodine concentrations of iohexol and iodixanol contrast media on image reconstruction techniques in a vascular-specific contrast media phantom: quantitative and qualitative image quality assessment.

La Radiologia medica
Charbel SaadeAlain S Abi-Ghanem

Abstract

The aim of our study is to investigate the impact of iodine quantification on image reconstruction when employing a vascular-specific contrast media phantom with varying iodine concentrations. A 30-cm phantom simulating arterial and venous blood vessel diameters was manufactured. Small (9 mm) and medium (12 mm) cylinders contained iodine concentrations from 10 to 100% while large (21 mm) cylinders were in quartiles from 25 to 100% diluted in blood equivalent medium. Each phantom was filled with either iohexol 350 mgI/mL (Group A) or iodixanol 320 mgI/mL (Group B) and then scanned separately. For each group, tube potential (80-140 kVp) and current (50-400 mAs) were changed and all image series were reconstructed with filtered back projection (FBP), hybrid-based iterative reconstruction (HBIR) and model-based iterative reconstruction (MBIR). Mean opacification was measured in all groups. All data were compared employing an independent t test and Pearson's correlation. Visual grading characteristic (VGC) and Cohens' kappa analyses were performed. At 80 kVp, mean opacification using HBIR was significantly higher in Group B (2165 ± 1108 HU) than in Group A (2040 ± 1036 HU) (p < 0.009). At 140 kVp, MBIR and HBIR were greater in Group...Continue Reading

References

May 4, 2005·Academic Radiology·Harpreet K PannuElliot K Fishman
Sep 21, 2013·Journal of Computer Assisted Tomography·Charbel SaadePatrick C Brennan
Jan 6, 2016·Diagnostic and Interventional Radiology : Official Journal of the Turkish Society of Radiology·Charbel SaadeFadi El-Merhi
Feb 9, 2017·European Radiology·Gert Jan PelgrimRozemarijn Vliegenthart
Jan 13, 2018·AJNR. American Journal of Neuroradiology·L SabaUNKNOWN Vessel Wall Imaging Study Group of the American Society of Neuroradiology
Sep 1, 2011·Journal of Medical Imaging and Radiation Sciences·Charbel SaadePatrick Brennan

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