PMID: 9524709Apr 3, 1998Paper

Impact on survival by method of recurrence detection in stage I and II cutaneous melanoma

Annals of Surgical Oncology
M M MooneyW G Kraybill

Abstract

The impact on survival by components of a surveillance program (physical examination, blood tests, and chest radiograph) used to detect recurrences in patients with cutaneous melanoma was assessed. Data were collected from medical records and tumor registry information on a historical cohort of 1004 patients who presented with AJCC Stage I or II cutaneous melanoma at Roswell Park Cancer Institute from 1971 through 1995. Information on method of detection was available on 154 out of 174 identified first recurrences (89%). Physical examination detected 72% of recurrences, constitutional symptoms indicated 17% of recurrences, and chest radiograph revealed 11% of recurrences. Blood tests did not predict any recurrence. Only 9 of 17 patients with recurrences detected by chest radiograph alone underwent curative surgical resection. These patients had a statistically significant prolonged survival after diagnosis of recurrence compared to those surgical candidates who did not undergo resection. There was no statistically significant difference in overall survival between patients with asymptomatic pulmonary recurrences and those whose pulmonary recurrences were detected after symptoms of metastatic disease had developed. Most recurren...Continue Reading

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Citations

Oct 12, 2013·Annals of Surgical Oncology·Christopher P Scally, Sandra L Wong
Nov 22, 2019·Current Radiopharmaceuticals·Riccardo LaudicellaAndrei Iagaru
Nov 28, 2002·International Journal of Dermatology·Tsu-Yi ChuangEvan R Farmer
Feb 20, 2014·International Journal of Clinical Practice·N J MarcianoJ M Street
Jan 1, 2010·Cancers·Ryan G GambleRobert P Dellavalle
Mar 12, 2013·ISRN Dermatology·J A Moreno NogueiraR Pérez Temprano
Jul 13, 2002·American Journal of Clinical Dermatology·Pearon G Lang
Sep 15, 2000·Plastic and Reconstructive Surgery·K S VirgoF E Johnson
Jul 24, 2015·AJR. American Journal of Roentgenology·Powell PerngRathan M Subramaniam
Aug 31, 2011·Dermatology Research and Practice·Yan XingJanice N Cormier
Mar 18, 2003·Seminars in Oncology Nursing·Lynne A LambWen-Jen Hwu
Aug 2, 2005·The Lancet Oncology·Anne Brecht FranckenHarald J Hoekstra

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