Impact on the medical decision-making process of multiplex PCR assay for respiratory pathogens

Epidemiology and Infection
A GuillonL Grammatico-Guillon

Abstract

The objective of this study was to determine how clinicians make use of the modern multiplex PCR assays (MPAs) to manage patients hospitalized for community-acquired pneumonia (CAP). We studied the use of MPAs in 1648 patients hospitalized for CAP over a 3-year period at the moment of the setup of the new PCR assay. We observed that the use of MPAs for the identification of multiple respiratory pathogens marks a radical change in the investigation of CAP etiology. Surprisingly, the contribution of MPAs to the medical decision-making process varies drastically according to the units of care.

References

Jan 17, 2012·Revue D'épidémiologie Et De Santé Publique·L Grammatico-GuillonE Rusch
Jan 5, 2013·Intensive Care Medicine·Laetitia ContentinDominique Perrotin
Feb 7, 2014·The New England Journal of Medicine·Richard G Wunderink, Grant W Waterer
Sep 4, 2015·Critical Care Medicine·Jean-Louis VincentUNKNOWN Rapid Diagnosis of Infections in the Critically Ill Team
Jan 10, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Naomi J GadsbyKate E Templeton
Jun 2, 2016·European Respiratory Review : an Official Journal of the European Respiratory Society·Michael BurkRodrigo Cavallazzi

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Citations

Aug 17, 2018·Annals of Intensive Care·Lucile LaporteAntoine Guillon
Jan 20, 2021·Revue des maladies respiratoires·S PilletA Vabret
Dec 4, 2020·European Respiratory Review : an Official Journal of the European Respiratory Society·Antoine GuillonLeslie Grammatico-Guillon

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