Impacts of low level aflatoxin in feed and the use of modified yeast cell wall extract on growth and health of nursery pigs

Animal Nutrition
Yawang SunSung Woo Kim

Abstract

This study was to investigate the effect of corn naturally contaminated with aflatoxins (AF) under the regulatory level on the growth performance and health of nursery pigs, and the efficiency of yeast cell wall based feed additive (YC) mainly composed of β-glucans and mannan oligosaccharide (MOS) (Integral A+, Alltech, Lexington, KY) in prevention of mycotoxicosis. Pigs (60 barrows and 60 gilts at 6.02 ± 0.83 kg BW) were randomly allotted to 4 treatments in a randomized complete block design based on a 2 × 2 factorial arrangement with 10 pens (5 barrow and 5 gilt pens) per treatment and 3 pigs per pen. Pigs were fed experimental diets for 5 wk. First factor was AF (0 or 20 µg/kg in feed) and the second factor was YC (0 or 2 g/kg in feed). Feed intake and body weight were measured weekly, and blood samples were used to measure blood cell counts, immunoglobulin G (IgG), tumor necrosis factor-a (TNF-a), oxidative damage status, and serological evaluation related to liver health. Aflatoxin decreased (P < 0.05) the number of platelet count (247.4 to 193.5 × 103/µL), and it also tended to increase the level of albumin (P = 0.055, 3.46 to 3.63 g/dL), albumin:globulin ratio (P = 0.050, 2.09 to 2.37), and Ca (P = 0.080, 10.79 to 10.97 ...Continue Reading

Citations

Dec 24, 2019·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Hong PengGuangtao Zhang
Jun 26, 2020·Frontiers in Immunology·Kristen A ByrneJodi L McGill
Jul 27, 2020·Translational Animal Science·Joice V San AndresThomas E Burkey
Feb 5, 2021·Antioxidants·Alexandros MavrommatisKostas Feggeros
Mar 2, 2021·Frontiers in Veterinary Science·Lan ZhengSung Woo Kim
Nov 5, 2021·Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan·Kenji OonakaYoshiko Sugita-Konishi

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