Impaired Facilitatory Mechanisms of Auditory Attention After Damage of the Lateral Prefrontal Cortex

Cerebral Cortex
Aurélie Bidet-CauletRobert T Knight

Abstract

There is growing evidence that auditory selective attention operates via distinct facilitatory and inhibitory mechanisms enabling selective enhancement and suppression of sound processing, respectively. The lateral prefrontal cortex (LPFC) plays a crucial role in the top-down control of selective attention. However, whether the LPFC controls facilitatory, inhibitory, or both attentional mechanisms is unclear. Facilitatory and inhibitory mechanisms were assessed, in patients with LPFC damage, by comparing event-related potentials (ERPs) to attended and ignored sounds with ERPs to these same sounds when attention was equally distributed to all sounds. In control subjects, we observed 2 late frontally distributed ERP components: a transient facilitatory component occurring from 150 to 250 ms after sound onset; and an inhibitory component onsetting at 250 ms. Only the facilitatory component was affected in patients with LPFC damage: this component was absent when attending to sounds delivered in the ear contralateral to the lesion, with the most prominent decreases observed over the damaged brain regions. These findings have 2 important implications: (i) they provide evidence for functionally distinct facilitatory and inhibitory me...Continue Reading

References

Jun 1, 1990·Biological Psychology·P T MichieL C Glue
Jan 1, 1987·Electroencephalography and Clinical Neurophysiology·F PerrinJ F Echallier
Feb 1, 1989·Electroencephalography and Clinical Neurophysiology·F PerrinJ F Echallier
Oct 1, 1980·Electroencephalography and Clinical Neurophysiology·R T KnightH J Neville
Dec 1, 1981·Electroencephalography and Clinical Neurophysiology·R T KnightH J Neville
Jun 29, 1981·Brain Research·P Müller-Preuss, D Ploog
Nov 1, 1994·Perception & Psychophysics·C Alain, D L Woods
Jun 20, 1998·Journal of Cognitive Neuroscience·L L Chao, R T Knight
Jul 8, 1998·Proceedings of the National Academy of Sciences of the United States of America·J JonidesP A Reuter-Lorenz
Mar 7, 2000·Frontiers in Bioscience : a Journal and Virtual Library·M H GiardJ Pernier
Mar 22, 2000·Nature Neuroscience·F BarcelóR T Knight
Jun 9, 2000·Annual Review of Neuroscience·S Kastner, L G Ungerleider
Apr 18, 2002·Brain Research. Cognitive Brain Research·William J Gehring, Robert T Knight
May 10, 2002·Journal of Experimental Psychology. Human Perception and Performance·Robert D MelaraYunxia Tong
Jan 22, 2003·Nature Neuroscience·Adam R AronTrevor W Robbins
Jan 13, 2004·Science·Michael C AndersonJohn D E Gabrieli
Apr 27, 2005·Cognitive, Affective & Behavioral Neuroscience·Elena YagoRobert T Knight
Jun 14, 2005·Consciousness and Cognition·Hamid Reza Naghavi, Lars Nyberg
Sep 15, 2005·Nature Neuroscience·Adam GazzaleyMark D'Esposito
Aug 31, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Aurélie Bidet-CauletOlivier Bertrand
Jul 5, 2008·The European Journal of Neuroscience·Alexander DegermanKimmo Alho
Sep 4, 2008·Proceedings of the National Academy of Sciences of the United States of America·Adam GazzaleyMark D'Esposito
Jan 14, 2009·Experimental Brain Research·Scott SinnettAlan Kingstone
Apr 29, 2009·Neuropsychologia·Jesse RissmanMark D'Esposito
Jul 1, 2010·Journal of Cognitive Neuroscience·Brian T MillerMark D'Esposito
Jul 17, 2010·Neuropsychologia·Maria ChaitJonathan Z Simon
May 31, 2011·Nature Neuroscience·James Z Chadick, Adam Gazzaley
Jun 21, 2011·Computational Intelligence and Neuroscience·Pierre-Emmanuel AgueraOlivier Bertrand

❮ Previous
Next ❯

Citations

Aug 19, 2017·Proceedings of the National Academy of Sciences of the United States of America·Elif IsbellHelen J Neville
Jul 2, 2020·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Hiroyuki FujiiNoriko Sato

❮ Previous
Next ❯

Related Concepts

Related Feeds

Attention Disorders

Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.