Impaired glucose metabolism in heroin and methadone users

Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme
A CerielloF D'Onofrio

Abstract

Plasma glucose and insulin responses to both oral and intravenous glucose stimulation were evaluated in heroin and methadone addicts, compared to healthy control subjects. Both groups of addicts had an altered response to oral and intravenous glucose load. These phenomena were linked to a reduced insulin response. Moreover, increased fasting insulin levels in both groups of addicts were observed. These data show that both heroin and methadone addiction may alter glucose metabolism, and, furthermore, stress the findings of similarities between opiate addicts and non-insulin dependent diabetics.

Citations

Jun 1, 2006·Journal of Urban Health : Bulletin of the New York Academy of Medicine·Rakhi KohliHenry S Sacks
Jan 1, 1997·General Pharmacology·D SadavaD P Pettit-Barrett
Mar 2, 2010·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Andrea A HowardPhyllis C Tien
Mar 26, 2011·Journal of Opioid Management·David J MyselsMaria A Sullivan
Jun 7, 2012·Digestive Diseases and Sciences·Donna L WhiteHashem B El-Serag
Apr 22, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Andrea A HowardEllie E Schoenbaum
Mar 8, 2013·Cellular and Molecular Neurobiology·Andrew J FaskowitzGavril W Pasternak
Feb 9, 2012·Drug and Chemical Toxicology·Albert Stuart Reece
Jun 26, 2013·The American Journal on Addictions·Ayman FareedLawrence Phillips
Jun 20, 2015·Acta Anaesthesiologica Scandinavica·J Gjedsted, R Dall
Oct 12, 2010·Medical Hypotheses·Albert Stuart Reece
Jan 20, 2017·Current Diabetes Reports·Kimberly N WalterNancy M Petry
May 1, 2012·Journal of Clinical Psychopharmacology·Erin N UmbergDavid J Greenblatt
Dec 7, 2017·Journal of Psychopharmacology·Stephen DanielsFrancesco Leri
Aug 5, 2017·Substance Abuse : Official Publication of the Association for Medical Education and Research in Substance Abuse·Gabriel VallecilloJuan Pedro-Botet

❮ Previous
Next ❯

Related Concepts

Related Feeds

Addiction

This feed focuses mechanisms underlying addiction and addictive behaviour including heroin and opium dependence, alcohol intoxication, gambling, and tobacco addiction.