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Impaired lymph node stromal cell function during the earliest phases of rheumatoid arthritis

Arthritis Research & Therapy

Feb 28, 2018

Janine HähnleinL G M van Baarsen

Abstract

Systemic autoimmunity can be present years before clinical onset of rheumatoid arthritis (RA). Adaptive immunity is initiated in lymphoid tissue where lymph node stromal cells (LNSCs) regulate immune responses through their intimate connection with leucocytes. We postulate that malfunct...read more

Mentioned in this Paper

Tumor Necrosis Factor-alpha
Protein Domain
Recombinant Secondary Lymphoid-Tissue Chemokine
Recombinant Cytokines
Stromal Cell-Derived Factor 1
Recombinant Tumor Necrosis Factor-Beta
Peripheral Blood
Leukocytes
Nongranular Leukocyte
Ligands
1
13
Paper Details
References
  • References40
  • Citations1
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Impaired lymph node stromal cell function during the earliest phases of rheumatoid arthritis

Arthritis Research & Therapy

Feb 28, 2018

Janine HähnleinL G M van Baarsen

PMID: 29482663

DOI: 10.1186/s13075-018-1529-8

Abstract

Systemic autoimmunity can be present years before clinical onset of rheumatoid arthritis (RA). Adaptive immunity is initiated in lymphoid tissue where lymph node stromal cells (LNSCs) regulate immune responses through their intimate connection with leucocytes. We postulate that malfunct...read more

Mentioned in this Paper

Tumor Necrosis Factor-alpha
Protein Domain
Recombinant Secondary Lymphoid-Tissue Chemokine
Recombinant Cytokines
Stromal Cell-Derived Factor 1
Recombinant Tumor Necrosis Factor-Beta
Peripheral Blood
Leukocytes
Nongranular Leukocyte
Ligands
1
13

Similar Papers Found In These Feeds

Related Papers

Paper Details
References
  • References40
  • Citations1
1234
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