PMID: 8614778Jan 1, 1995Paper

Impaired neutrophil chemotaxis after cardiac surgery

Scandinavian Journal of Thoracic and Cardiovascular Surgery
R H JensenN Obel

Abstract

Chemotaxis of circulating peripheral neutrophils was studied in 12 patients undergoing elective cardiac surgery. Tests of neutrophil chemotaxis were made preoperatively and 16-20 hours postoperatively, using a multipore filter assay. Statistically significant postoperative decrease was demonstrated in both stimulated and random neutrophil migration (p = 0.012 and p = 0.009, respectively). Although the peripheral neutrophil count showed a statistically significant postoperative increase (p = 0.001), the increase did not correlate to the decrease in neutrophil chemotaxis. Nor could correlation be demonstrated between the altered neutrophil chemotaxis and any per- or postoperative variables.

References

Sep 1, 1976·Anesthesia and Analgesia·T H StanleyH R Hill
Feb 1, 1977·British Journal of Anaesthesia·G C MoudgilP C Wilkinson
Apr 1, 1992·Acta Anaesthesiologica Scandinavica·M Salo
Mar 1, 1986·The British Journal of Surgery·J P DuignanD Bouchier-Hayes
Oct 1, 1982·Acta Orthopaedica Scandinavica·M EndlerC Zielinski
May 1, 1981·Canadian Anaesthetists' Society Journal·G C MoudgilD J Ludlow

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