Impaired postural balance correlates with complex walking performance in mildly disabled persons with multiple sclerosis

NeuroRehabilitation
John BrincksUlrik Dalgas

Abstract

It is relevant to understand the possible influence of impaired postural balance on walking performance in multiple sclerosis (MS) gait rehabilitation. We expected associations between impaired postural balance and complex walking performance in mildly disabled persons with MS, but not in healthy controls. Thirteen persons with MS (Expanded Disability Status Scale = 2.5) and 13 healthy controls' walking performance were measured at fast walking speed, Timed Up & Go and Timed 25 Feet Walking. Postural balance was measured by stabilometry, 95% confidence ellipse sway area and sway velocity. Except from sway velocity (p = 0.07), significant differences were found between persons with MS and healthy controls in postural balance and walking. Significant correlations were observed between sway area and Timed Up & Go (r = 0.67) and fastest safe walking speed (r = -0.63) in persons with MS but not in healthy controls (r = 0.52 and r = 0.24, respectively). No other significant correlations were observed between postural balance and walking performance in neither persons with MS nor healthy controls. Findings add to the understanding of postural balance and walking in persons with MS, as impaired postural balance was related to complex w...Continue Reading

References

Oct 12, 1999·Multiple Sclerosis : Clinical and Laboratory Research·M G BenedettiS Giannini
Sep 28, 2000·The New England Journal of Medicine·J H NoseworthyB G Weinshenker
Nov 13, 2004·Gait & Posture·J A RaymakersH J J Verhaar
Jul 19, 2005·Annual Review of Neuroscience·Alvaro Pascual-LeoneLotfi B Merabet
Dec 24, 2005·Disability and Rehabilitation·Sema SavciRana Karabudak
Nov 8, 2006·Multiple Sclerosis : Clinical and Laboratory Research·C L MartinM P Galea
Sep 19, 2007·Clinical Rehabilitation·D CattaneoA Regola
Oct 11, 2008·Multiple Sclerosis : Clinical and Laboratory Research·D Cattaneo, J Jonsdottir
Feb 17, 2009·Clinical Rehabilitation·Y NilsagårdL-G Gunnarsson
Mar 3, 2009·Lancet·Andrew D GoodmanUNKNOWN Fampridine MS-F203 Investigators
Feb 13, 2010·Multiple Sclerosis : Clinical and Laboratory Research·Luca ProsperiniCarlo Pozzilli
Feb 17, 2010·Disability and Rehabilitation·Kevin John KelleherDimitrios Apatsidis
Mar 9, 2010·Multiple Sclerosis : Clinical and Laboratory Research·Domien GijbelsPeter Feys
Jun 23, 2010·Current Neurology and Neuroscience Reports·Michelle H Cameron, Stephen Lord
Aug 4, 2010·International Journal of Rehabilitation Research. Internationale Zeitschrift Für Rehabilitationsforschung. Revue Internationale De Recherches De Réadaptation·Cecilie FjeldstadMichael Bemben
Apr 16, 2011·Annals of Physical and Rehabilitation Medicine·A YahiaM H Elleuch
May 31, 2011·Multiple Sclerosis : Clinical and Laboratory Research·J C E KempenH Beckerman
Jul 23, 2011·Current Neurology and Neuroscience Reports·Michelle H Cameron, Joanne M Wagner
Oct 7, 2011·Journal of Applied Biomechanics·Jessie M HuisingaNicholas Stergiou
May 9, 2012·Multiple Sclerosis : Clinical and Laboratory Research·Tom BroekmansPeter Feys
Jun 29, 2012·Multiple Sclerosis : Clinical and Laboratory Research·Bernd C Kieseier, Carlo Pozzilli
Jul 25, 2012·Neuroscience Letters·Jessie M HuisingaNicholas Stergiou
Aug 28, 2012·Journal of Applied Biomechanics·Jessie M HuisingaNicholas Stergiou
Mar 28, 2013·Multiple Sclerosis International·Michael J Socie, Jacob J Sosnoff
Oct 8, 2013·Journal of the Neurological Sciences·Alon Kalron, Anat Achiron
Oct 8, 2013·Archives of Physical Medicine and Rehabilitation·Phu D HoangStephen R Lord
Nov 7, 2013·Journal of Neuroscience Methods·Neeta KanekarAlexander S Aruin
May 6, 2014·Neurorehabilitation and Neural Repair·Nora E FritzKathleen M Zackowski
Jun 11, 2014·Journal of Neuroengineering and Rehabilitation·Davide CattaneoRoberta Carabalona
Jul 9, 2014·Archives of Physical Medicine and Rehabilitation·Ylva Elisabet NilsagårdAnette Susanne Forsberg
Aug 15, 2014·International Journal of Rehabilitation Research. Internationale Zeitschrift Für Rehabilitationsforschung. Revue Internationale De Recherches De Réadaptation·Michael J SocieJacob J Sosnoff
Nov 14, 2014·Multiple Sclerosis : Clinical and Laboratory Research·Giampaolo BrichettoAndrea Tacchino

❮ Previous
Next ❯

Citations

Aug 29, 2020·Journal of Foot and Ankle Research·Minna StoltHelena Leino-Kilpi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.