PMID: 11335696May 4, 2001Paper

Impaired spatial working memory across saccades contributes to abnormal search in parietal neglect

Brain : a Journal of Neurology
Masud HusainC Kennard

Abstract

Visual neglect of left space following right parietal damage in humans involves a lateral bias in attention, apparent in many search tasks. We hypothesized that parietal neglect may also involve a failure to remember which locations have already been examined during visual search: an impairment in retaining searched locations across saccades. Using a new paradigm, we monitored gaze during search, while simultaneously probing whether observers judged they had found a new target, or judged instead that they were re-fixating a previously examined target. A patient with left neglect following focal right parietal infarction repeatedly re-fixated right locations. Critically, he often failed to remember that these locations had already been searched, treating old targets as new discoveries at an abnormal rate. In comparison, healthy age-matched control subjects rarely re-fixated targets, and mistook old targets as new targets even more rarely. The frequency of such mistakes in the parietal patient, for different conditions, correlated with the severity of his neglect. Control experiments indicated no perceptual localization deficit in non-search tasks. These results suggest a deficit in retaining searched locations across saccades in...Continue Reading

Citations

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Jun 11, 2005·Neuropsychologia·Susanne Ferber, James Danckert
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Oct 28, 2004·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Paresh MalhotraMasud Husain
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