PMID: 3768659Oct 1, 1986Paper

Impaired spermatogenesis in testes at risk of torsion

The British Journal of Surgery
J B AndersonR C Williamson

Abstract

The oligospermia observed after unilateral torsion of the spermatic cord could reflect immunological damage to the opposite testis. An alternative explanation, that there may be a pre-existing defect in spermatogenesis, was tested in 20 post-pubertal males with acute torsion. In a prospective study the contralateral testis was biopsied at operation and the histological appearances were related to subsequent testicular function as assessed by seminal analysis 3 months later. Thirteen patients had biopsy evidence of partial maturation arrest in spermatogenesis which was either mild (6), moderate (4) or severe (3), and ten of these were oligospermic (less than 20 X 10(6)/ml). By contrast all seven patients with normal histology had a sperm concentration greater than 25 X 10(6)/ml. Histological grading of spermatogenesis by the Johnsen technique gave a higher score in patients with a normal biopsy (median 9.01, semi-quartile range 8.96-9.21) than in those with abnormal histology (median 8.28, semi-quartile range 7.98-8.45, P less than 0.001) and correlated with the log of the sperm concentration 3 months later (r = 0.79, P less than 0.001). There was minimal anti-sperm and no anti-testis antibody formation following torsion. Serum ...Continue Reading

References

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Citations

Apr 1, 1994·Journal of Pediatric Surgery·G TryfonasM Badouraki
May 1, 1989·British Journal of Urology·F C TanyelA Hiçsönmez
Aug 12, 2014·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Manuel NistalMiguel Reyes-Múgica
Jan 1, 1993·Scandinavian Journal of Urology and Nephrology·K BrassoJ Egense
Aug 11, 2020·Pediatric Surgery International·Kolja KvistJorgen Thorup

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