PMID: 6982087Oct 1, 1982Paper

Impaired T-cell and NK-cell function in patients with preleukemia

Blut
F Porzsolt, H Heimpel

Abstract

The responses to the T-cell mitogens Phythemagglutinin (PHA) and Concanavalin A (Con A) and the natural killer (NK) cell activity are tested in patients with preleukemia (PL). The results are compared with those of healthy controls. The PL patients show low responses to T-cell mitogens and low NK cell activities. It is discussed that the data are not of prognostic value in PL as to development of overt leukemia. However, the results suggest that PL impaired cell functions are not limited to erythropoiesis, granulopoiesis, and thrombopoiesis but are also found in the immune system.

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Citations

Dec 1, 1983·Immunobiology·F PorzsoltH Heimpel
Feb 1, 1993·Leukemia Research·K OgataT Nomura
Jan 11, 1992·Critical Reviews in Oncology/hematology·P Noël, L A Solberg
Jan 1, 1984·British Journal of Haematology·P ColombatG Renoux
Jan 1, 1989·Journal of Clinical Laboratory Analysis·C C Paul, M A Baumann
Jan 16, 2007·Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi·Kiyoyuki Ogata
Jan 20, 2012·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Stefania VaraniCecilia Söderberg-Nauclér
Mar 15, 1988·Cancer·P H ColombatG Renoux

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