PMID: 11605790Oct 19, 2001Paper

Impaired urinary water excretion in a three-generation family

Pediatric Nephrology : Journal of the International Pediatric Nephrology Association
Y TanakaT Ogata

Abstract

We report on a three-generation family (daughter, mother, and maternal grandmother) with a syndrome of inappropriate secretion of antidiuretic hormone (SIADH)-like condition in the absence of inappropriate ADH secretion. In the three females, a water load test showed severely reduced urinary water excretion, with the ratio of urine volume to the loaded water being 10-33% (normal value: 70.2 +/- 7.8%). Urinary AQP2 excretion was normal, as was the DNA sequence of AVPR2 and AQP2. The results suggest the presence of a new dominantly inherited disorder for tubular water resorption.

Citations

Nov 23, 2006·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·David Francisco BesElvira Arrizurieta
Feb 12, 2010·International Journal of Pediatric Endocrinology·Yoon Hi ChoGeoffrey Ambler
Jun 16, 2009·Seminars in Nephrology·David B Mount
Jun 16, 2009·Seminars in Nephrology·Guy Decaux
Jul 18, 2006·The American Journal of Medicine·Stephen E GitelmanStephen M Rosenthal
Jan 21, 2006·The Journal of Pediatrics·Eric A HuangStephen E Gitelman
Jan 19, 2007·Journal of the American Society of Nephrology : JASN·Guy DecauxCatheline Vilain
Apr 10, 2019·Journal of the American Society of Nephrology : JASN·Mami MiyadoTsutomu Ogata

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The New England Journal of Medicine
Brian J FeldmanStephen E Gitelman
Pediatric Nephrology : Journal of the International Pediatric Nephrology Association
Maria Antonietta MarcialisMaria Cristina Rosatelli
© 2021 Meta ULC. All rights reserved