Impairment in emotional modulation of attention and memory in schizophrenia

Schizophrenia Research
Julie Walsh-MessingerDolores Malaspina

Abstract

Emotion plays a critical role in cognition and goal-directed behavior via complex interconnections between the emotional and motivational systems. It has been hypothesized that the impairment in goal-directed behavior widely noted in schizophrenia may result from defects in the interaction between the neural (ventral) emotional system and (rostral) cortical processes. The present study examined the impact of emotion on attention and memory in schizophrenia. Twenty-five individuals with schizophrenia related psychosis and 25 healthy control subjects were administered a computerized task in which they were asked to search for target images during a Rapid Serial Visual Presentation of pictures. Target stimuli were either positive or negative, or neutral images presented at either 200ms or 700ms lag. Additionally, a visual hedonic task was used to assess differences between the schizophrenia group and controls on ratings of valence and arousal from the picture stimuli. Compared to controls, individuals with schizophrenia detected fewer emotional images under both the 200ms and 700ms lag conditions. Multivariate analyses showed that the schizophrenia group also detected fewer positive images under the 700ms lag condition and fewer n...Continue Reading

References

Mar 1, 1992·Archives of General Psychiatry·S M Resnick
Oct 1, 1990·The Journal of Nervous and Mental Disease·R U WeinerN Papouchis
Jan 1, 1995·Annual Review of Neuroscience·R Desimone, J Duncan
Feb 1, 1995·Journal of Experimental Psychology. Human Perception and Performance·M M Chun, M C Potter
Dec 22, 1998·Brain Research. Brain Research Reviews·K C Berridge, T E Robinson
Aug 9, 2002·Neuroreport·Chiang-shan Ray LiYing-cheng Chen
Oct 3, 2002·The American Journal of Psychiatry·Rita Z Goldstein, Nora D Volkow
Nov 9, 2002·Science·R J Dolan
Jan 12, 2005·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Darin P SmithAaron R Duley
Dec 2, 2005·Annual Review of Psychology·Elizabeth A Phelps
Mar 18, 2006·Cognitive, Affective & Behavioral Neuroscience·Elaine FoxGeorge A Georgiou
Apr 25, 2006·Behavior Research Methods·Joseph A MikelsPatricia A Reuter-Lorenz
Aug 8, 2006·Journal of Psychiatric Research·Jonathan K WynnMichael F Green
Sep 30, 2006·Cognitive, Affective & Behavioral Neuroscience·Elizabeth A Kensinger, Daniel L Schacter
May 10, 2007·Journal of Cognitive Neuroscience·Sang Hee Kim, Stephan Hamann
May 23, 2007·Journal of Abnormal Psychology·Erin A Heerey, James M Gold
Nov 9, 2007·Journal of Autism and Developmental Disorders·Ben CordenDavid Skuse
Dec 7, 2007·Archives of General Psychiatry·Raquel E GurRuben C Gur
Mar 8, 2008·Memory & Cognition·Karen J MathewsonCraig A Mansfield
Jun 27, 2008·Schizophrenia Bulletin·Ann M Kring, Erin K Moran
Oct 10, 2008·Schizophrenia Bulletin·Gabriel S DichterAysenil Belger
Nov 13, 2009·Schizophrenia Research·Fabien TrémeauDaniel C Javitt
Jan 6, 2011·The American Journal of Psychiatry·Stefan UrsuCameron S Carter
Nov 1, 1997·Trends in Cognitive Sciences·K L ShapiroK M Arnell
May 10, 2011·Journal of Psychiatric Research·Kristopher I MathisMichael F Green
Dec 12, 2012·Acta Psychiatrica Scandinavica·S Dieleman, C H Röder
Feb 21, 2013·Journal of Abnormal Psychology·Gregory P StraussJames M Gold

Related Concepts

Vigilance, Cortical
Mental Concentration
Computers, Digital
Regret
Memory
Memory for Designs Test
Photic Stimulation
Schizophreniform Disorders
Schizophrenia
Schizophrenic Psychology

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