Impedance spectroscopic investigation of the bilayer lipid membranes formed from the phosphatidylserine-ceramide mixture.

The Journal of Membrane Biology
Monika Naumowicz, Zbigniew A Figaszewski

Abstract

Electrochemical impedance spectroscopy was used for the study of two-component lipid membranes. Phosphatidylserine and ceramide were to be investigated because they play an important biochemical role in cell membranes. The research on biolipid interaction was focused on a quantitative description of processes that take part in a bilayer. Assumed models of interaction between amphiphilic molecules and the equilibria that take place there were described by mathematical equations for the studied system. The possibility of complex formation for a two-component system forming bilayers was assumed, which could explain the deviation from the additivity rule. The molecular area and the equilibrium constant of the complex were determined.

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Dec 4, 2003·Bioelectrochemistry·Monika Naumowicz, Zbigniew Figaszewski
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Aug 30, 2005·Biophysical Journal·Monika Naumowicz, Zbigniew A Figaszewski
Oct 26, 2005·The Journal of Membrane Biology·M Naumowicz, Z A Figaszewski
Sep 2, 2006·Biochimica Et Biophysica Acta·Joke A Bouwstra, Maria Ponec

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