Implantable cardioverter defibrillators in patients with electrical heart disease and hypertrophic cardiomyopathy: data from the German device registry

Clinical Research in Cardiology : Official Journal of the German Cardiac Society
Gerrit FrommeyerLars Eckardt

Abstract

Implantable cardioverter- defibrillator (ICD) therapy is established for the prevention of sudden cardiac death (SCD) in different entities. However, data from large patient cohorts with electrical heart disease are rare. Therefore, we investigated these patients as well as patients with hypertrophic cardiomyopathy by analyzing registry data from a multi-center 'real-life' registry. The German Device Registry (DEVICE) is a nationwide, prospective registry with one-year follow-up investigating 5450 patients receiving device implantations in 50 German centers. The present analysis of DEVICE focussed on patients with electrical heart disease or HCM who received an ICD for primary or secondary prevention. 174 patients with HCM and 112 patients with electrical heart disease (long-QT syndrome, Brugada syndrome and arrhythmogenic right ventricular cardiomyopathy) were compared with 5164 other ICD patients. Median follow-up was 17.0 months. Patients in the control group were significantly older. Of note, overall mortality after 1 year was 1.8% in HCM patients, 6.6% in patients with electrical heart disease and 7.3% in the control group. Patients in the control group presented significantly more severe comorbidities. In contrast to HCM ...Continue Reading

References

Mar 22, 2002·The New England Journal of Medicine·Arthur J MossUNKNOWN Multicenter Automatic Defibrillator Implantation Trial II Investigators
May 21, 2004·The New England Journal of Medicine·Alan KadishUNKNOWN Defibrillators in Non-Ischemic Cardiomyopathy Treatment Evaluation (DEFINITE) Investigators
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Oct 8, 2011·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Gerold MönnigLars Eckardt
Aug 4, 2015·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Gerrit FrommeyerFlorian Reinke
Oct 27, 2016·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Gerrit FrommeyerFlorian Reinke
Jun 9, 2017·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Giuseppe D'AnconaJasmin Ortak
Nov 22, 2017·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Mate VamosStefan H Hohnloser
Jun 11, 2018·International Journal of Cardiology·Gerrit FrommeyerHans Gerd Kehl
Mar 25, 2019·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Kevin WillyGerrit Frommeyer

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Citations

Nov 2, 2019·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Kevin WillyGerrit Frommeyer
Dec 12, 2019·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Harilaos BogossianBernd Lemke
Apr 3, 2020·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Tobias SchuppMichael Behnes
Feb 2, 2020·Herzschrittmachertherapie & Elektrophysiologie·Lars Eckardt

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