Implantation of amniotic membrane as a vascular substitute in the external jugular vein of juvenile sheep

Journal of Vascular Surgery
Habibollah PeiroviHassan Niknejad

Abstract

Amniotic membrane, as a natural biomaterial, has many advantages, such as low immunogenicity, anti-inflammation, antifibrosis, and rich extracellular matrix components, which make it a promising source for vascular tissue engineering. This study assessed the feasibility of constructing a vein conduit from the amniotic membrane and implanting it in the external jugular vein of juvenile sheep. Human amniotic membrane was prepared using fresh human placenta. For construction of a tube such as a vein, the membrane was rolled around a tube and amniotic membrane-constructed conduits were interposed to the external jugular vein by end-to-end anastomosis. Grafts were assessed for patency at weeks 5 and 48 and explanted for evaluation with histologic and microscopic techniques. At 5 weeks after implantation, the grafts were completely patent and displayed no signs of dilation. The internal surface was smooth and shiny, without any evidence of thrombus formation. After 48 weeks, grafts were still completely patent and displayed no signs of intimal thickening, dilation, or stenosis. No inflammation or fibrosis was evident. Histologic evaluation of the explanted grafts demonstrated a monolayer of endothelial cells. Scanning electron micros...Continue Reading

References

Oct 29, 1998·Cellular and Molecular Life Sciences : CMLS·M L Rose
Mar 13, 2003·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·John CarnageyChristine E Schmidt
Sep 13, 2003·The Journal of Clinical Endocrinology and Metabolism·Anne E KingRodney W Kelly
Feb 27, 2004·Investigative Ophthalmology & Visual Science·Yutaka IshinoShigeru Kinoshita
Aug 6, 2005·Stem Cells·Toshio MikiStephen C Strom
May 12, 2007·Journal of Reproductive Immunology·Toshio MikiStephen C Strom
May 15, 2007·Biology of Reproduction·Sivakami IlancheranUrsula Manuelpillai

❮ Previous
Next ❯

Citations

Jun 19, 2013·Current Opinion in Biotechnology·Daniel D Swartz, Stelios T Andreadis
Mar 8, 2013·Placenta·H NiknejadH Peirovi
Oct 9, 2015·Tissue Engineering. Part B, Reviews·Samand Pashneh-TalaFrederik Claeyssens
Jul 21, 2015·Journal of Tissue Engineering and Regenerative Medicine·Mona KakavandHassan Niknejad
May 23, 2015·Medical Hypotheses·Hassan NiknejadMona Kakavand
Aug 31, 2013·Cryobiology·Fatemeh A TehraniHassan Niknejad
Dec 10, 2016·PloS One·Sabreen KhalilNoha Mousa
Dec 7, 2018·Expert Opinion on Biological Therapy·Jan AdamowiczTomasz Drewa
Oct 13, 2018·Tissue Engineering. Part B, Reviews·Shigeo IchihashiPetra Mela
May 31, 2018·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Süleyman OrmanFatma Eyüboğlu
Feb 2, 2021·Frontiers in Bioengineering and Biotechnology·Adelheid WeidingerAsmita Banerjee
Mar 11, 2020·Oncology Reviews·Ameneh JafariHakimeh Zali
Jul 22, 2019·Journal of the Mechanical Behavior of Biomedical Materials·Agathe GrémareNicolas L'Heureux
Jun 3, 2021·Membranes·Mathilde FénelonFlorelle Gindraux
Jul 9, 2018·ACS Biomaterials Science & Engineering·Julien H Arrizabalaga, Matthias U Nollert
Dec 9, 2020··Ernie Maduratna SetyawatiOkkinardo Arief

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Adult Stem Cells

Adult stem cells reside in unique niches that provide vital cues for their survival, self-renewal, and differentiation. They hold great promise for use in tissue repair and regeneration as a novel therapeutic strategies. Here is the latest research.

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis