Implausible States: Prevalence of EQ-5D-5L States in the General Population and Its Effect on Health State Valuation.

Medical Decision Making : an International Journal of the Society for Medical Decision Making
Ole MartenAki Tsuchiya

Abstract

The EQ-5D is made up of health state dimensions and levels, in which some combinations seem less "plausible" than others. If "implausible" states are used in health state valuation exercises, then respondents may have difficulty imagining them, causing measurement error. There is currently no standard solution: some valuation studies exclude such states, whereas others leave them in. This study aims to address 2 gaps in the literature: 1) to propose an evidence-based set of the least prevalent two-way combinations of EQ-5D-5L dimension levels and 2) to quantify the impact of removing perceived implausible states from valuation designs. For the first aim, we use data from 2 waves of the English General Practitioner Patient Survey (n = 1,639,453). For the second aim, we remodel a secondary data set of a Discrete Choice Experiment (DCE) with duration that valued EQ-5D-5L and compare across models that drop observations involving different health states: 1) implausible states as defined in the literature, 2) the least prevalent states identified in stage 1, and 3) randomly select states, alongside 4) a model that does not drop any observations. The results indicate that two-way combinations previously thought to be implausible actu...Continue Reading

References

Nov 21, 1997·Medical Care·P Dolan
Jun 6, 1996·Health Policy·R Brooks
Apr 10, 2002·Journal of Health Economics·John BrazierMark Deverill
Jun 19, 2009·Scandinavian Journal of Public Health·Jan SørensenHenrik Brønnum-Hansen
Apr 12, 2011·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·M HerdmanX Badia
Sep 15, 2011·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Rosalie VineyJulie Ratcliffe
Dec 27, 2011·Journal of Health Economics·Nick BansbackAslam Anis
Feb 2, 2013·Health and Quality of Life Outcomes·Adrian Bagust
Jun 15, 2013·Health Economics·Rosalie VineyDeborah Street
Aug 8, 2013·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Andreas HinzElmar Brähler
Aug 27, 2013·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Kristina BurströmNiklas Zethraeus
Feb 27, 2014·Health Technology Assessment : HTA·Brendan MulhernAki Tsuchiya
Apr 11, 2014·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Jeff RichardsonMunir A Khan
Sep 24, 2014·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Sun SunKristina Burström
Nov 5, 2014·PloS One·Sanjeewa KularatnaPaul A Scuffham
Aug 9, 2016·Social Science & Medicine·M M Versteegh, W B F Brouwer
Sep 21, 2016·Health and Quality of Life Outcomes·Nikki McCaffreyJulie Ratcliffe
Sep 30, 2016·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Brendan MulhernAki Tsuchiya
Feb 2, 2017·Archives of Medical Science : AMS·Dominik Golicki, Maciej Niewada
Aug 24, 2017·Health Economics·Nancy J DevlinBen van Hout
Jul 7, 2019·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Zhihao YangNan Luo

❮ Previous
Next ❯

Citations

Sep 13, 2020·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·S R CopeN Agrawal

❮ Previous
Next ❯

Software Mentioned

Ngene
DCE

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research
Zhihao YangNan Luo
European Journal of Public Health
Fred Paccaud
BMJ : British Medical Journal
John P A Ioannidis
Wiener klinische Wochenschrift
Stephen Barrett
Journal of the American College of Cardiology
Colin BerryKeith G Oldroyd
© 2021 Meta ULC. All rights reserved