Implementation of 3 T lactate-edited 3D 1H MR spectroscopic imaging with flyback echo-planar readout for gliomas patients.

Annals of Biomedical Engineering
Ilwoo ParkS J Nelson

Abstract

The purpose of this study was to implement a new lactate-edited 3D 1H magnetic resonance spectroscopic imaging (MRSI) sequence at 3 T and demonstrate the feasibility of using this sequence for measuring lactate in patients with gliomas. A 3D PRESS MRSI sequence incorporating shortened, high bandwidth 180° pulses, new dual BASING lactate-editing pulses, high bandwidth very selective suppression (VSS) pulses and a flyback echo-planar readout was implemented at 3 T. Over-prescription factor of PRESS voxels was optimized using phantom to minimize chemical shift artifacts. The lactate-edited flyback sequence was compared with lactate-edited MRSI using conventional elliptical k-space sampling in a phantom and volunteers, and then applied to patients with gliomas. The results demonstrated the feasibility of detecting lactate within a short scan time of 9.5 min in both phantoms and patients. Over-prescription of voxels gave less chemical shift artifacts allowing detection of lactate on the majority of the selected volume. The normalized SNR of brain metabolites using the flyback encoding were comparable to the SNR of brain metabolites using conventional phase encoding MRSI. The specialized lactate-edited 3D MRSI sequence was able to de...Continue Reading

References

Nov 1, 1992·Journal of Computer Assisted Tomography·J V HajnalG M Bydder
Apr 1, 1991·NMR in Biomedicine·J W Prichard
Mar 1, 1988·Magnetic Resonance Imaging·J R MacFallR M Vavrek
Apr 1, 1996·NMR in Biomedicine·P E SijensM Oudkerk
May 20, 1999·Journal of Magnetic Resonance Imaging : JMRI·D A KelleyJ M Star-Lack
Nov 5, 1999·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·K P PruessmannP Boesiger
Jan 22, 2000·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·T K TranR Hurd
Jul 31, 2001·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·S J Nelson
Feb 24, 1956·Science·O WARBURG
Sep 28, 2005·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Charles H CunninghamJohn M Pauly
Nov 24, 2005·AJR. American Journal of Roentgenology·Patrick WeybrightLarry Junck
Apr 6, 2006·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Esin Ozturk-IsikSarah J Nelson
Sep 12, 2006·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Richard A E EddenPeter B Barker
Nov 10, 2006·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Ricardo OtazoStefan Posse
Sep 28, 2007·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Lana G KaiserGerald B Matson
Jan 1, 1991·IEEE Transactions on Medical Imaging·J PaulyA Macovski
Apr 5, 2008·European Radiology·Alfonso Di CostanzoGioacchino Tedeschi
Nov 26, 2008·Journal of Magnetic Resonance Imaging : JMRI·Mari A SmithKristen L Zakian
Sep 22, 2009·Magnetic Resonance Imaging·Esin Ozturk-IsikSarah J Nelson

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Citations

Jan 13, 2012·Science Translational Medicine·Adam ElkhaledSarah J Nelson
Mar 19, 2014·Acta Oncologica·Ioanna ChronaiouTone Frost Bathen
Apr 27, 2012·Journal of Magnetic Resonance Imaging : JMRI·Mary A McLeanJohn R Griffiths
Mar 25, 2015·NMR in Biomedicine·Geoffrey S PayneMartin O Leach
Jul 22, 2014·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Akshay MadanChangho Choi
Mar 5, 2013·Journal of Magnetic Resonance·Sarah J NelsonJason Crane
Feb 26, 2016·Neuro-oncology·Llewellyn E JalbertSarah J Nelson
Nov 4, 2015·Brain Pathology·Myriam M ChaumeilSabrina M Ronen
Mar 23, 2017·Scientific Reports·Llewellyn E JalbertSarah J Nelson
Jan 13, 2012·Cancer Biology & Therapy·Rui LiuXiubao Ren
May 14, 2020·NMR in Biomedicine·Wolfgang BognerAnke Henning
May 16, 2015·Brain Tumor Research and Treatment·Marc C MabraySoonmee Cha
Mar 31, 2015·The Cancer Journal·Yan LiSarah J Nelson
Sep 18, 2015·Molecular Cancer Therapeutics·Vlad C SandulacheStephen Y Lai

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