Implementation of a multidisciplinary antimicrobial stewardship programme in a Philippine tertiary care hospital: an evaluation by repeated point prevalence surveys.

Journal of Global Antimicrobial Resistance
Gina de Guzman BetitoMaria Tarcela Gler

Abstract

Optimising antimicrobial prescribing in hospitals through antimicrobial stewardship (AMS) is essential in addressing the global threat of antimicrobial resistance. The objective of this study was to evaluate the impact of a hospital-wide programme, delivered by a multidisciplinary AMS team, on antimicrobial prescribing outcomes. The AMS programme consisted of a combination of persuasive, restrictive, and structural components and was implemented in two phases. We used data from the Global-PPS, collected every six months between September 2017 and December 2019, to measure the antimicrobial use prevalence and monitor selected antibiotic prescribing quality indicators. A significantly increasing trend (P < 0.001) was observed for the indicators related to documentation of prescribing, that is the reason for treatment and stop or review date. We observed a significantly decreasing trend (P < 0.001) in the number of prescriptions for surgical antibiotic prophylaxis (SAP) prescribed for more than 24 h; however, sample sizes for surgical patients were small. For these three indicators, a sudden and pronounced improvement was seen after the second set of interventions, which consisted of (i) an antibiotic documentation policy, (ii) a ...Continue Reading

References

Oct 20, 2005·The Journal of Antimicrobial Chemotherapy·Marjo E E van KasterenInge C Gyssens
Oct 22, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Faranak AnsariPeter Davey
Nov 19, 2010·The Journal of Antimicrobial Chemotherapy·Peter ZarbUNKNOWN ESAC-3 Hospital Care Subproject Group
Sep 6, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Esmita CharaniAlison Holmes
Nov 23, 2012·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·P ZarbUNKNOWN Hospital Contact Points for the ECDC pilot point prevalence survey
Apr 11, 2013·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·E CharaniA Holmes
May 2, 2013·The Cochrane Database of Systematic Reviews·Peter DaveyMark Wilcox
Jan 30, 2015·The International Journal of Pharmacy Practice·Elaine RobertsChristopher Cefai
Apr 16, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Tamar F BarlamKavita K Trivedi
Apr 28, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Tamar F BarlamKavita K Trivedi
Jun 4, 2016·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·C VerchevalT Van Hees
Nov 1, 2016·Clinical Microbiology Reviews·Li-Yang HsuPaul Anantharajah Tambyah
Jun 3, 2017·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M E A de KrakerS Harbarth
Sep 30, 2017·The Journal of Antimicrobial Chemotherapy·Raphaël M ZellwegerUNKNOWN Southeast Asia Antimicrobial Resistance Network
Jun 7, 2019·The Journal of Hospital Infection·S K SinghA Versporten
Jul 30, 2020·Antibiotics·Svetlana Rachina Russian Global-Pps Project Study Group

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.