Implementation of closed-loop-assisted intra-operative goal-directed fluid therapy during major abdominal surgery: A case-control study with propensity matching

European Journal of Anaesthesiology
A JoostenPhilippe Van der Linden

Abstract

Goal-directed fluid therapy (GDFT) has been associated with improved patient outcomes. However, implementation of GDFT protocols remains low despite growing published evidence and the recommendations of multiple regulatory bodies in Europe. We developed a closed-loop-assisted GDFT management system linked to a pulse contour monitor to assist anaesthesiologists in applying GDFT. To assess the impact of our closed-loop system in patients undergoing major abdominal surgery in an academic hospital without a GDFT programme. A case-control study with propensity matching. Operating rooms, Erasme Hospital, Brussels. All patients who underwent elective open major abdominal surgery between January 2013 and December 2016. Implementation of our closed-loop-assisted GDFT in April 2015. A total of 104 patients managed with closed-loop-assisted GDFT were paired with a historical cohort of 104 consecutive non-GDFT patients. The historical control group consisted of patients treated before the implementation of the closed-loop-system, and who did not receive GDFT. In the closed-loop group, the system delivered a baseline crystalloid infusion of 3 ml kg h and additional 100 ml fluid boluses of either a crystalloid or colloid for haemodynamic opt...Continue Reading

References

Dec 24, 2008·Emergency Medicine Journal : EMJ·W R SpanjersbergI B Schipper
May 27, 2011·Anesthesia and Analgesia·Timothy E MillerTong J Gan
Aug 17, 2011·Critical Care : the Official Journal of the Critical Care Forum·Maxime CannessonAzriel Perel
Nov 25, 2011·Critical Care : the Official Journal of the Critical Care Forum·Joseph RinehartMaxime Cannesson
Apr 3, 2012·Journal for Specialists in Pediatric Nursing : JSPN·Fenella GillDianne Stewart
Jul 10, 2013·Anesthesia and Analgesia·Joseph RinehartGuy Dumont
Oct 16, 2013·Annales Françaises D'anesthèsie Et De Rèanimation·B ValletUNKNOWN Socie´te ´ franc ¸aise d’anesthe´sie et de re´animation
Jan 1, 2014·Annales Françaises D'anesthèsie Et De Rèanimation·J RinehartM Cannesson
Apr 19, 2015·Critical Care : the Official Journal of the Critical Care Forum·Joseph RinehartMaxime Cannesson
Apr 22, 2015·Perioperative Medicine·Lais Helena Camacho NavarroGeorge C Kramer
Sep 25, 2015·Critical Care : the Official Journal of the Critical Care Forum·Can Ince
Nov 19, 2015·Anaesthesiology Intensive Therapy·Alexandre JoostenMaxime Cannesson
Jan 6, 2016·Critical Care : the Official Journal of the Critical Care Forum·Can Ince

❮ Previous
Next ❯

Citations

Mar 1, 2019·European Journal of Anaesthesiology·David GreenEric Mills
Mar 1, 2019·European Journal of Anaesthesiology·Sean CoeckelenberghAlexandre Joosten
May 3, 2020·Anesthesiology·Kamal Maheshwari, Daniel I Sessler
Sep 27, 2019·Journal of Anesthesia·Sean CoeckelenberghAlexandre Joosten
Aug 21, 2020·BMC Anesthesiology·Alexandre JoostenPhilippe Van der Linden
Aug 25, 2018·Journal of Clinical Monitoring and Computing·Bernd SaugelThomas W L Scheeren
Dec 10, 2020·Der Anaesthesist·Marcus ThudiumMark Coburn
May 22, 2020·Journal of Cardiothoracic and Vascular Anesthesia·Joseph RinehartAlexandre Joosten
Jan 31, 2020·Intensive Care Medicine·Matthieu LegrandAlexandre Joosten
Apr 15, 2020·Anesthesia and Analgesia·Cédrick ZaouterThomas M Hemmerling
Dec 2, 2020·European Journal of Anaesthesiology·Sean CoeckelenberghPanayota Kapessidou
Oct 5, 2019·Best Practice & Research. Clinical Anaesthesiology·Brenton AlexanderAlexandre Joosten
Aug 17, 2021·Anesthesiology Clinics·Theodora WingertMaxime Cannesson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.