Implementation of multi-site neurocognitive assessments within a pediatric cooperative group: can it be done?

Pediatric Blood & Cancer
Leanne EmbryRobert B Noll

Abstract

Neurocognitive functioning is an important construct in childhood cancer survivorship, given the potential neurotoxicity of central nervous system (CNS) diseases and treatments and the relevance for important functional outcomes in adulthood. However, within pediatric oncology cooperative groups there have been significant barriers to neurocognitive data collection that have historically resulted in incomplete data (<30% compliance), thereby limiting progress in understanding the neurocognitive functioning of survivors. This paper describes the development, feasibility, and potential efficacy of a brief neurocognitive battery to maximize collection of psychometrically robust neurocognitive data within a pediatric cooperative group. We hypothesized that a novel set of procedures could result in collection of data from over 80% of eligible children. A novel assessment battery (ALTE07C1) that evaluates a child's cognitive, social, emotional, and behavioral functioning was developed. It included measures that were psychometrically sound, normed, widely available, and could be administered by any licensed psychologist. The battery required approximately 1 hour of administration time. A data monitoring team was developed to ensure pr...Continue Reading

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Citations

Jan 21, 2014·Journal of Pediatric Psychology·Mary Jo Kupst
Aug 1, 2014·Journal of the National Cancer Institute·Sharon M CastellinoBeverly J Lange
Jul 9, 2013·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Emilie F SmithsonMatthew C H J Morrall
Dec 21, 2012·Pediatric Blood & Cancer·Robert B NollUNKNOWN COG Behavioral Sciences Committee
Aug 19, 2015·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Gesche TallenUNKNOWN German Paediatric Brain Tumour Consortium (HIT-Network)
Jun 14, 2015·Child Neuropsychology : a Journal on Normal and Abnormal Development in Childhood and Adolescence·Katie Olson, Stephen A Sands
Nov 19, 2013·International Journal of Radiation Oncology, Biology, Physics·Colin KennedyUNKNOWN PNET4 study group of the Brain Tumour Group of The European branch of the International Society of Paediatric Oncology (SIOP
Jan 7, 2014·Cancer Treatment Reviews·N U GerberS Rutkowski
Jan 27, 2015·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Jennifer A LimondUNKNOWN Brain Tumour Quality of Survival Group, International Society of Paediatric Oncology (Europe) (SIOP-E)
Jan 27, 2015·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Holger OttensmeierStefan Rutkowski
Jul 30, 2015·Journal of Pediatric Oncology Nursing : Official Journal of the Association of Pediatric Oncology Nurses·Mary Baron NelsonRonald M Harper
Jul 23, 2013·Journal of Pediatric Oncology Nursing : Official Journal of the Association of Pediatric Oncology Nurses·Troy C QuiggNerissa S Bauer
Jan 27, 2016·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Stephen A Sands
Sep 24, 2019·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jason FangusaroGirish Dhall
Jul 25, 2019·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·J KhalilN Benjaafar
Jun 11, 2021·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jeff M MichalskiPaul A Northcott

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