Implementation of Rotavirus Surveillance and Vaccine Introduction - World Health Organization African Region, 2007-2016

MMWR. Morbidity and Mortality Weekly Report
Jason M MwendaUmesh D Parashar

Abstract

Rotavirus is a leading cause of severe pediatric diarrhea globally, estimated to have caused 120,000 deaths among children aged <5 years in sub-Saharan Africa in 2013 (1). In 2009, the World Health Organization (WHO) recommended rotavirus vaccination for all infants worldwide (2). Two rotavirus vaccines are currently licensed globally: the monovalent Rotarix vaccine (RV1, GlaxoSmithKline; 2-dose series) and the pentavalent RotaTeq vaccine (RV5, Merck; 3-dose series). This report describes progress of rotavirus vaccine introduction (3), coverage (using estimates from WHO and the United Nations Children's Fund [UNICEF]) (4), and impact on pediatric diarrhea hospitalizations in the WHO African Region. By December 2016, 31 (66%) of 47 countries in the WHO African Region had introduced rotavirus vaccine, including 26 that introduced RV1 and five that introduced RV5. Among these countries, rotavirus vaccination coverage (completed series) was 77%, according to WHO/UNICEF population-weighted estimates. In 12 countries with surveillance data available before and after vaccine introduction, the proportion of pediatric diarrhea hospitalizations that were rotavirus-positive declined 33%, from 39% preintroduction to 26% following rotavirus...Continue Reading

References

Dec 18, 2013·The Pediatric Infectious Disease Journal·Jason M MwendaDeo Nshimirimana
Apr 10, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jacqueline E TateUNKNOWN World Health Organization–Coordinated Global Rotavirus Surveillance Network
Apr 22, 2017·The Journal of Infectious Diseases·Eleanor BurnettUmesh D Parashar

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Citations

Jun 4, 2019·Human Vaccines & Immunotherapeutics·Federico Martinón-TorresRobb Butler
Jul 19, 2019·Journal of the Pediatric Infectious Diseases Society·Andi L Shane, Geoffrey A Weinberg
Jun 6, 2021·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jason M MwendaJacqueline E Tate

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